Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …
Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved
Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …
Adverse effects of cancer chemotherapy: Anything new to improve tolerance and reduce sequelae?
The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …
source of concern for both patients and clinicians despite the improved efficacy and …
New insights toward colorectal cancer chemotherapy using natural bioactive compounds
S Redondo-Blanco, J Fernández… - Frontiers in …, 2017 - frontiersin.org
Combination therapy consists in the simultaneous administration of a conventional
chemotherapy drug (or sometimes, a radiotherapy protocol) together with one or more …
chemotherapy drug (or sometimes, a radiotherapy protocol) together with one or more …
The PI3K/Akt/mTOR axis in colorectal cancer: oncogenic alterations, non‐coding RNAs, therapeutic opportunities, and the emerging role of nanoparticles
MJ Sanaei… - Journal of Cellular …, 2022 - Wiley Online Library
Colorectal cancer (CRC) is one of the deadliest human malignancies worldwide. Several
molecular pathways have been demonstrated to be involved in the initiation and …
molecular pathways have been demonstrated to be involved in the initiation and …
Isoflavones, their glycosides and glycoconjugates. Synthesis and biological activity
W Szeja, G Grynkiewicz, A Rusin - Current Organic Chemistry, 2017 - ingentaconnect.com
Glycosylation of small biologically active molecules, either of natural or synthetic origin, has
a profound impact on their solubility, stability, and bioactivity, making glycoconjugates …
a profound impact on their solubility, stability, and bioactivity, making glycoconjugates …
[HTML][HTML] Genistein inhibits human colorectal cancer growth and suppresses miR-95, Akt and SGK1
J Qin, JX Chen, Z Zhu, JA Teng - Cellular physiology and biochemistry, 2015 - karger.com
Background: Genistein, a major isoflavonoid isolated from dietary soybean, has been shown
to suppress the growth of several cancers through modulation of various pathways …
to suppress the growth of several cancers through modulation of various pathways …
[HTML][HTML] The synergism of natural compounds and conventional therapeutics against colorectal cancer progression and metastasis
Z Liang, H Xie, W Shen, L Shao, L Zeng… - Frontiers in Bioscience …, 2022 - imrpress.com
Cancer progression and metastases are the leading causes of poor outcomes in patients
with colon cancer. Colon cancer metastasis is a multigene, multistep, multistage complex …
with colon cancer. Colon cancer metastasis is a multigene, multistep, multistage complex …
Dalbergia sissoo phytochemicals as EGFR inhibitors: an in vitro and in silico approach
HN Naik, D Kanjariya, S Parveen, A Meena… - Journal of …, 2023 - Taylor & Francis
The safest and most effective sources of medications are natural and traditional medicines
derived from plants and herbs. In Western India, various parts of the Dalbergia sissoo plant …
derived from plants and herbs. In Western India, various parts of the Dalbergia sissoo plant …
Apigenin inhibits growth of breast cancer cells: the role of ERα and HER2/neu
AM Scherbakov, OE Andreeva - Acta Naturae (англоязычная …, 2015 - cyberleninka.ru
Phytoestrogens are a group of plant-derived compounds with an estrogen-like activity. In
mammalians, phytoestrogens bind to the estrogen receptor (ER) and participate in the …
mammalians, phytoestrogens bind to the estrogen receptor (ER) and participate in the …