Fertility preservation in boys: recent developments and new insights

E Goossens, K Jahnukainen, RT Mitchell… - Human …, 2020 - academic.oup.com
BACKGROUND Infertility is an important side effect of treatments used for cancer and other
non-malignant conditions in males. This may be due to the loss of spermatogonial stem cells …

[HTML][HTML] What should be done in terms of fertility preservation for patients with cancer? The French 2021 guidelines

N Rives, B Courbière, T Almont, D Kassab… - European Journal of …, 2022 - Elsevier
Aim To provide practice guidelines about fertility preservation (FP) in oncology. Methods We
selected 400 articles after a PubMed review of the literature (1987–2019) …

Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation

C Wyns, M Kanbar, MG Giudice… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

Male fertility preservation and restoration strategies for patients undergoing gonadotoxic therapies

KTD Tran, H Valli-Pulaski, A Colvin… - Biology of …, 2022 - academic.oup.com
Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

[HTML][HTML] Fertility after curative therapy for sickle cell disease: a comprehensive review to guide care

RS Nickel, JY Maher, MH Hsieh, MF Davis… - Journal of clinical …, 2022 - mdpi.com
Curative therapy for sickle cell disease (SCD) currently requires gonadotoxic conditioning
that can impair future fertility. Fertility outcomes after curative therapy are likely affected by …

[HTML][HTML] Generation of organized porcine testicular organoids in solubilized hydrogels from decellularized extracellular matrix

M Vermeulen, F Del Vento, M Kanbar… - International Journal of …, 2019 - mdpi.com
Cryopreservation of immature testicular tissue (ITT) prior to chemo/radiotherapy is now
ethically accepted and is currently the only way to preserve fertility of prepubertal boys about …

[HTML][HTML] Testicular tissue banking for fertility preservation in young boys: which patients should be included?

E Delgouffe, A Braye, E Goossens - Frontiers in Endocrinology, 2022 - frontiersin.org
Due to the growing number of young patients at risk of germ cell loss, there is a need to
preserve spermatogonial stem cells for patients who are not able to bank spermatozoa …

[HTML][HTML] Preservation of fertility in female and male prepubertal patients diagnosed with cancer

MI Albamonte, AD Vitullo - Journal of Assisted Reproduction and Genetics, 2023 - Springer
Over the past two decades, the importance of fertility preservation has grown not only in the
realm of medical and clinical patient care, but also in the field of basic and applied research …

Cancer cell contamination and decontamination methods for ovaries and testes: special focus on prepubertal gonads with a view to safe fertility restoration

D Kourta, M Kanbar, CA Amorim… - Human Reproduction, 2023 - academic.oup.com
Fertility restoration in patients that survived a hematological cancer during childhood is a
core part of their care pathway. Nonetheless, there might be a risk of contamination of the …

Long-term follow-up of boys who have undergone a testicular biopsy for fertility preservation

M Kanbar, F De Michele, MG Giudice… - Human …, 2021 - academic.oup.com
STUDY QUESTION What is the long-term reproductive health outcome of patients who have
undergone testicular sampling for fertility preservation (FP) before and during the pubertal …