Preclinical evidence has firmly established bidirectional interactions among the brain, the
gut, and the gut microbiome. Candidate signaling molecules and at least three …

Background Irritable bowel syndrome (IBS) is one of the most common functional bowel
disorders, but community prevalence appears to vary widely between different countries …

Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders
seen by clinicians in both primary and secondary care. Since publication of the last British …

Chemical tools that allow the real-time monitoring of organ function and the visualisation of
organ-related processes at the cellular level are of great importance in biological research …

Background & Aims Although functional gastrointestinal disorders (FGIDs), now called
disorders of gut-brain interaction, have major economic effects on health care systems and …

Irritable bowel syndrome (IBS) results from disordered brain–gut interactions. Identifying
susceptibility genes could highlight the underlying pathophysiological mechanisms. We …

Importance The prevalence of irritable bowel syndrome (IBS) in the United States is between
7% and 16%, most common in women and young people, with annual direct costs estimated …

Up to 20% of people worldwide develop gastrointestinal symptoms following a meal, leading
to decreased quality of life, substantial morbidity and high medical costs. Although the …

Background & Aims Irritable bowel syndrome (IBS) is a common disorder of gut–brain
interaction associated with significant disease burden. This American Gastroenterological …

Irritable bowel syndrome (IBS) is one of the most common disorders of gut–brain interaction
worldwide, defined according to patterns of gastrointestinal symptoms as described by the …