Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus
E Sanchez, A Nadig, BC Richardson… - Annals of the …, 2011 - ard.bmj.com
Objective Systemic lupus erythematosus is a clinically heterogeneous autoimmune disease.
A number of genetic loci that increase lupus susceptibility have been established. This study …
A number of genetic loci that increase lupus susceptibility have been established. This study …
Genetic admixture and asthma‐related phenotypes in Mexican American and Puerto Rican asthmatics
Genetic association studies in admixed populations may be biased if individual ancestry
varies within the population and the phenotype of interest is associated with ancestry …
varies within the population and the phenotype of interest is associated with ancestry …
[PDF][PDF] Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels
Circulating levels of inflammatory markers can predict cardiovascular disease risk. To
identify genes influencing the levels of these markers, we genotyped 1,343 single …
identify genes influencing the levels of these markers, we genotyped 1,343 single …
[PDF][PDF] Prospects for admixture mapping of complex traits
PM McKeigue - The American Journal of Human Genetics, 2005 - cell.com
Admixture mapping extends to human populations the principles that underlie linkage
analysis of an experimental cross. For detecting genes that contribute to ethnic variation in …
analysis of an experimental cross. For detecting genes that contribute to ethnic variation in …
[HTML][HTML] Ancestry analysis in the 11-M Madrid bomb attack investigation
The 11-M Madrid commuter train bombings of 2004 constituted the second biggest terrorist
attack to occur in Europe after Lockerbie, while the subsequent investigation became the …
attack to occur in Europe after Lockerbie, while the subsequent investigation became the …
The complex genetics of multiple sclerosis: pitfalls and prospects
S Sawcer - Brain, 2008 - academic.oup.com
The genetics of complex disease is entering a new and exciting era. The exponentially
growing knowledge and technological capabilities emerging from the human genome …
growing knowledge and technological capabilities emerging from the human genome …
[HTML][HTML] Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium
While genome-wide association studies (GWAS) have primarily examined populations of
European ancestry, more recent studies often involve additional populations, including …
European ancestry, more recent studies often involve additional populations, including …
Examination of ancestry and ethnic affiliation using highly informative diallelic DNA markers: application to diverse and admixed populations and implications for …
We and others have identified several hundred ancestry informative markers (AIMs) with
large allele frequency differences between different major ancestral groups. For this study, a …
large allele frequency differences between different major ancestral groups. For this study, a …
The ethnic/racial variations of intracerebral hemorrhage (ERICH) study protocol
D Woo, J Rosand, C Kidwell, JL McCauley, J Osborne… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Epidemiological studies of intracerebral hemorrhage (ICH) have
consistently demonstrated variation in incidence, location, age at presentation, and …
consistently demonstrated variation in incidence, location, age at presentation, and …
[HTML][HTML] Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with a strong
genetic component. African-Americans (AA) are at increased risk of SLE, but the genetic …
genetic component. African-Americans (AA) are at increased risk of SLE, but the genetic …