Adipose-derived stromal/stem cells (ASCs) seems to be a promising regenerative
therapeutic agent due to the minimally invasive approach of their harvest and multi-lineage …

Bone tissue engineering has been one of the most promising areas of research, providing a
potential clinical application to cure bone defects. Recently, various stem cells including …

Mesenchymal stem cells (MSCs) were first isolated more than 50 years ago from the bone
marrow. Currently MSCs may also be isolated from several alternative sources and they …

Background Parry-Romberg disease is a rare condition that results in progressive hemifacial
atrophy, involving the skin, dermis, subcutaneous fat, muscle, and, finally, cartilage and …

While small bone defects heal spontaneously, large bone defects need surgical intervention
for bone transplantation. Autologous bone grafts are the best and safest strategy for bone …

One of the most important issues in orthopaedic surgery is the loss of bone resulting from
trauma, infections, tumours or congenital deficiency. In view of the hypothetical future …

While bone marrow-derived mesenchymal stem cells are known and have been
investigated for a long time, mesenchymal stem cells derived from the adipose tissue were …

Adipose-derived stem cells (ASCs) and mesenchymal stem cells are promising for tissue
repair because of their multilineage differentiation capacity. Our previous data confirmed that …

Background aims Several authors have demonstrated that adipose tissue contains
multipotent cells capable of differentiation into several lineages, including bone, cartilage …

We have previously shown that elevating extracellular calcium from a concentration of 1.8 to
8 mM accelerates and increases human adipose-derived stem cell (hASC) osteogenic …