VeSPA: integrated applications for RF pulse design, spectral simulation and MRS data analysis

BJ Soher, P Semanchuk, D Todd, X Ji… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose The Vespa package (Versatile Simulation, Pulses, and Analysis) is described and
demonstrated. It provides workflows for developing and optimizing linear combination …

Feasibility and implications of using subject‐specific macromolecular spectra to model short echo time magnetic resonance spectroscopy data

HJ Zöllner, CW Davies‐Jenkins… - NMR in …, 2023 - Wiley Online Library
Expert consensus recommends linear‐combination modeling (LCM) of 1H MR spectra with
sequence‐specific simulated metabolite basis function and experimentally derived …

CloudBrain-MRS: An intelligent cloud computing platform for in vivo magnetic resonance spectroscopy preprocessing, quantification, and analysis

X Chen, J Li, D Chen, Y Zhou, Z Tu, M Lin… - Journal of Magnetic …, 2024 - Elsevier
Magnetic resonance spectroscopy (MRS) is an important clinical imaging method for
diagnosis of diseases. MRS spectrum is used to observe the signal intensity of metabolites …

Brain Glutathione and GABA+ levels in autistic children

Y Song, KE Hupfeld, CW Davies‐Jenkins… - Autism …, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social
communication challenges and repetitive behaviors. Altered neurometabolite levels …

[HTML][HTML] Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease

AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …

Glutamate measurements using edited MRS

MG Saleh, A Prescot, L Chang, C Cloak… - Magnetic resonance …, 2024 - Wiley Online Library
Purpose To demonstrate J‐difference coediting of glutamate using Hadamard encoding and
reconstruction of Mescher‐Garwood‐edited spectroscopy (HERMES). Methods Density …

J-difference GABA-edited MRS reveals altered cerebello-thalamo-cortical metabolism in patients with hepatic encephalopathy

HJ Zöllner, TA Thiel, ND Füllenbach, MS Jördens… - Metabolic Brain …, 2023 - Springer
Hepatic encephalopathy (HE) is a common neurological manifestation of liver cirrhosis and
is characterized by an increase of ammonia in the brain accompanied by a disrupted …

Brain total creatine differs between primary progressive aphasia (PPA) subtypes and correlates with disease severity

KE Hupfeld, HJ Zöllner, G Oeltzschner, HW Hyatt… - Neurobiology of …, 2023 - Elsevier
Primary progressive aphasia (PPA) is comprised of three subtypes: logopenic (lvPPA), non-
fluent (nfvPPA), and semantic (svPPA). We used magnetic resonance spectroscopy (MRS) …

Impact of acquisition and modeling parameters on the test–retest reproducibility of edited GABA+

KE Hupfeld, HJ Zöllner, SCN Hui, Y Song… - NMR in …, 2024 - Wiley Online Library
Literature values vary widely for within‐subject test–retest reproducibility of gamma‐
aminobutyric acid (GABA) measured with edited magnetic resonance spectroscopy (MRS) …

sLASER and PRESS perform similarly at revealing metabolite‐age correlations at 3 T

SCN Hui, HJ Zöllner, T Gong… - Magnetic resonance …, 2024 - Wiley Online Library
Purpose To compare the respective ability of PRESS and sLASER to reveal biological
relationships, using age as a validation covariate at 3 T. Methods MRS data were acquired …