[HTML][HTML] Immunotherapeutic potential of T memory stem cells

Y Li, D Wu, X Yang, S Zhou - Frontiers in oncology, 2021 - frontiersin.org
Memory T cells include T memory stem cells (TSCM) and central memory T cells (TCM).
Compared with effector memory T cells (TEM) and effector T cells (TEFF), they have better …

[HTML][HTML] Intersection of two checkpoints: could inhibiting the DNA damage response checkpoint rescue immune checkpoint-refractory cancer?

PH Goff, R Bhakuni, T Pulliam, JH Lee, ET Hall… - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapies have revolutionized the management of advanced stage
cancer; however, not all patients benefit given many cancers are resistant to immune …

Doxorubicin-loaded platelet decoys for enhanced chemoimmunotherapy against triple-negative breast cancer in mice model

H Dong, M Gao, L Lu, R Gui, Y Fu - International Journal of …, 2023 - Taylor & Francis
Introduction Triple-negative breast cancer (TNBC) is a highly aggressive subtype with a poor
prognosis. Current single-agent checkpoint therapy has limited effectiveness in TNBC …

[HTML][HTML] Immunology of cell death in cancer immunotherapy

L Galluzzi, AD Garg - Cells, 2021 - mdpi.com
Over the last two decades, a large volume of studies has established that dying and dead
cancer cells exert a potent immunomodulatory effect on their immediate microenvironment …

[HTML][HTML] Chemoimmunotherapy combinations: translating basic knowledge into clinical successes

L Apetoh - Genes & Immunity, 2024 - nature.com
While chemotherapeutic agents were long solely associated with immunosuppression,
clinical data demonstrate that the combination of some chemotherapies with …

Harnessing Th9 cells in cancer immunotherapy

I Benoit-Lizon, L Apetoh - Seminars in Immunology, 2021 - Elsevier
CD4 T cell effector subsets not only profoundly affect cancer progression, but recent
evidence also underscores their critical contribution to the anticancer efficacy of immune …

[HTML][HTML] La voie de signalisation de STING dans les lymphocytes T: applications potentielles en immunothérapie anticancéreuse

L Apetoh - Bulletin de l'Académie Nationale de Médecine, 2022 - Elsevier
Résumé Les succès obtenus dans le domaine de l'immunothérapie anticancéreuse grâce
aux inhibiteurs des points de contrôle immunitaire montrent que la capacité des cellules du …