Follicular helper T cells in the immunopathogenesis of SARS-CoV-2 infection

D Cui, Y Tang, Q Jiang, D Jiang, Y Zhang, Y Lv… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a serious infectious disease that has led to a …

Biology and clinical relevance of follicular cytotoxic T cells

Y Lv, L Ricard, B Gaugler, H Huang, Y Ye - Frontiers in Immunology, 2022 - frontiersin.org
Follicular cytotoxic T (Tfc) cells are a newly identified subset of CD8+ T cells enriched in B
cell follicles and their surroundings, which integrate multiple functions such as killing …

Astragaloside IV ameliorates pulmonary vascular remodeling in hypoxia-induced pulmonary hypertension by restraining the T follicular helper cell response and …

C Li, H Zhu, S Zhang, F Meng, S Li, G Li, J Zha, S Wu… - Phytomedicine, 2022 - Elsevier
Background Pulmonary hypertension (PH) is a progressive disorder lacking a validated and
effective therapy which characterized by elevated pulmonary arterial pressure, vascular …

New insights into follicular regulatory T cells in the intestinal and tumor microenvironments

Y Cao, Y Hou, L Zhao, Y Huang… - Journal of Cellular …, 2023 - Wiley Online Library
Follicular regulatory T (Tfr) cells are a novel and unique subset of effector regulatory T (Treg)
cells that are located in germinal centers (GCs). Tfr cells express transcription profiles that …

Esophageal cancer cell-derived small extracellular vesicles decrease circulating Tfh/Tfr via sEV-PDL1 to promote immunosuppression

Z Li, Y Zhang, H Hao, L Chen, T Lv, X Zhang… - Cancer Immunology …, 2023 - Springer
Esophageal cancer (EC) is a deadly malignancy. Small extracellular vesicles (sEVs) with
programmed death ligand 1 (sEV-PDL1) induce immune escape to promote tumor …

[HTML][HTML] The Role of Regulatory T Cells in Allergic Diseases: Collegium Internationale Allergologicum (CIA) Update 2024

L Martín-Cruz, C Benito-Villalvilla, S Sirvent… - … Archives of Allergy and …, 2024 - karger.com
Background: Allergy represents a major health problem of increasing prevalence worldwide
with a high socioeconomic impact. Our knowledge on the molecular mechanisms underlying …

Dysregulated Tfr/Tfh2 cells in patients with polycystic ovarian syndrome

X Xuan, C Ye, J Zhao, F Shen, Y Chen, J Liu - Journal of Reproductive …, 2023 - Elsevier
Recent research revealed the pathogenic role of B cells in the pathogenesis of polycystic
ovary syndrome (PCOS), while the Tfh cell plays a critical role in the B cell mediated …

Esophageal cancer derived exosomes imbalance circulating Tfh/Tfr via EXO-PDL1 to promote immunosuppression

Z Li, Y Zhang, H Hao, L Chen, T Lv, X Zhang, Y Qi… - 2023 - researchsquare.com
Background: Esophageal cancer (EC) is a deadly malignancy. Exosomal programmed
death ligand 1 (EXO-PDL1) induces immune escape to promote tumor progression …

Esophageal cancer-derived exosomes imbalance Tfh/Tfr cell ratio in the tumor immune microenvironment via EXO-PDL1 to promote immunosuppression

Z Li, Y Zhang, H Hao, T Lv, X Zhang, L Chen, Y Qi… - 2023 - researchsquare.com
Background: Esophageal cancer (EC) is a deadly malignancy. Exosomal programmed
death ligand 1 (EXO-PDL1) induces immune escape to promote tumor progression …