Isolation of naturally occurring novel isoflavonoids: An update

N Al-Maharik - Natural product reports, 2019 - pubs.rsc.org
Covering: Jan. 2012 to Dec. 2017 This review describes the 391 new isoflavonoids isolated
and identified from natural sources between January 2012 and December 2017 …

The pharmacology of the genus Sophora (Fabaceae): An updated review

SH Aly, AM Elissawy, OA Eldahshan, MA Elshanawany… - Phytomedicine, 2019 - Elsevier
Abstract Background The genus Sophora (Fabaceae) represents one of the important
medicinal plant genera regarding its chemical constituents and outstanding …

Quinolizidine Alkaloids with Antiviral and Insecticidal Activities from the Seeds of Sophora tonkinensis Gagnep

J Zou, L Zhao, P Yi, Q An, L He, Y Li… - Journal of Agricultural …, 2020 - ACS Publications
The discovery of novel, effective, and botanical pesticides is one of the main strategies for
modern plant protection and insect pest control. During the search for novel botanical …

Prenylated Flavonoids from the Roots and Rhizomes of Sophora tonkinensis and Their Effects on the Expression of Inflammatory Mediators and Proprotein …

J Ahn, YM Kim, HS Chae, YH Choi… - Journal of natural …, 2019 - ACS Publications
Seven new prenylated flavonoids (1–7) and one new prenylated phenylpropiophenone (8)
were isolated from roots and rhizomes of Sophora tonkinensis, along with nine known …

Quinolizidine alkaloids from Sophora tonkinensis and their anti-inflammatory activities

LJ He, JS Liu, D Luo, YR Zheng, YB Zhang, GC Wang… - Fitoterapia, 2019 - Elsevier
Two new quinolizidine-based alkaloids (2 and 12), along with ten known ones (1, 3–11)
were isolated from the roots of S. tonkinensis. Their structures were determined by …

Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma

XF Zhu, ZL Sun, J Ma, B Hu, MC Yu, XJ Liu… - Phytotherapy …, 2023 - Wiley Online Library
Abstract Sorafenib (SF), a multi‐kinase inhibitor, is the first FDA‐approved systemic
chemotherapy drug for advanced hepatocellular carcinoma (HCC). However, its clinical …

[HTML][HTML] Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of …

M Hou, W Hu, Z Xiu, A Jiang, L Men, K Hao, X Sun… - Molecules, 2019 - mdpi.com
For the full development and utilization of Sophora tonkinensis Gagnep., this study was
primarily intended to established a simple and efficient approach for the preparative …

A Review of Pharmacological and Toxicological Effects of Sophora tonkinensis with Bioinformatics Prediction

SN Zhang, XZ Li, LY Tan, KY Zhu - The American Journal of …, 2021 - World Scientific
Sophora tonkinensis Gagnep.(ST)(Fabaceae) is distributed chiefly in south-central and
southeast China and Vietnam. In traditional Chinese medicine theory, the root and rhizome …

Natural products as IL‐6 inhibitors for inflammatory diseases: Synthetic and SAR perspective

DS Harmalkar, A Sivaraman, H Nada… - Medicinal Research …, 2024 - Wiley Online Library
Abstract Interleukin‐6 (IL‐6), a pleiotropic cytokine, plays a pivotal role in the
pathophysiology of various diseases including diabetes, atherosclerosis, Alzheimer's …

A review on the relationship of mast cells and macrophages in breast cancer—Can herbs or natural products facilitate their anti-tumor effects?

L Gou, GGL Yue, PT Puno, C Bik-San Lau - Pharmacological research, 2021 - Elsevier
Breast cancer is an inflammation-related cancer whose tumor microenvironment is largely
infiltrated by inflammatory cells. These inflammatory cells including mast cells and …