New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022

JS Jiang, Y Wang, M Deng - Frontiers in pharmacology, 2022 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that
primarily affects motor neurons in the brain and spinal cord. In the recent past, there have …

Update on transfusion-related acute lung injury: an overview of its pathogenesis and management

Y Yu, Z Lian - Frontiers in Immunology, 2023 - frontiersin.org
Transfusion-related acute lung injury (TRALI) is a severe adverse event and a leading cause
of transfusion-associated death. Its poor associated prognosis is due, in large part, to the …

The Expression of FOXO3a as a Forensic Diagnostic Tool in Cases of Traumatic Brain Injury: An Immunohistochemical Study

A Maiese, F Spina, G Visi, F Del Duca… - International Journal of …, 2023 - mdpi.com
Traumatic brain injury (TBI) is one of the most well-known causes of neurological impairment
and disability in the world. The Forkhead Box class O (FOXO) 3a is a transcription factor that …

Mechanisms of autoimmune cell in DA neuron apoptosis of Parkinson's disease: recent advancement

Z Zheng, S Zhang, H Zhang, Z Gao… - Oxidative Medicine …, 2022 - Wiley Online Library
Parkinson's disease (PD) is a prevalent neurodegenerative disorder that manifests as motor
and nonmotor symptoms due to the selective loss of midbrain DArgic (DA) neurons. More …

Exploration of novel biomarkers in Alzheimer's disease based on four diagnostic models

C Zou, L Su, M Pan, L Chen, H Li, C Zou… - Frontiers in Aging …, 2023 - frontiersin.org
Background Despite tremendous progress in diagnosis and prediction of Alzheimer's
disease (AD), the absence of treatments implies the need for further research. In this study …

Bioinformatics analysis of CMTM family in pan-cancer and preliminary exploration of CMTM6 in bladder cancer

Y Xu, Q Li, H Lin - Cellular Signalling, 2024 - Elsevier
Background The chemokine-like factor (CKLF)-like Marvel transmembrane structural domain
(CMTM) family is widely expressed in the tumor and immune systems and is essential in …

Abnormal immune function of B lymphocyte in peripheral blood of Parkinson's disease

Z Zhang, X Xie, Y Cai, P Liu, S Liu, R Chen… - Parkinsonism & Related …, 2023 - Elsevier
Background Parkinson's disease (PD) is associated with peripheral inflammation and
abnormal peripheral blood lymphocyte immune responses. Peripheral blood B-lymphocyte …

Upregulation of Inflammatory Mediators in Peripheral Blood CD40+ Cells in Children with Autism Spectrum Disorder

AA Aldossari, MA Ansari, A Nadeem, SM Attia… - International Journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a common and severe neurodevelopmental disorder in
early childhood, defined as social and communication deficits and repetitive and stereotypic …

T cell activation via the CD40 ligand and transferrin receptor and deficits in T regulatory cells are associated with major depressive disorder and severity of depression

M Rachayon, K Jirakran, P Sodsai, A Sughondhabirom… - medRxiv, 2023 - medrxiv.org
Major depressive disorder (MDD) is associated with T cell activation (Maes et al. 1990-
1993), but no studies have examined the combined effects of T cell activation and deficits in …

T cell activation and deficits in T regulatory cells are associated with major depressive disorder and severity of depression

M Rachayon, K Jirakran, P Sodsai… - Scientific Reports, 2024 - nature.com
Major depressive disorder (MDD) is associated with T cell activation, but no studies have
examined the combined effects of T cell activation and deficits in T regulatory (Treg) cells on …