Stroke ranks second as a leading cause of death and permanent disability globally.
Microglia, innate immune cells in the brain, respond rapidly to ischemic injury, triggering a …

Considerable evidence supports that cytokines are important mediators of pathophysiologic
processes within the central nervous system (CNS). Numerous studies have documented …

Background Central nervous system diseases are associated with hypoxia, which usually
cause irreversible nerve damage, but the underlying mechanism is unclear and effective …

Oxidative stress and inflammation are two phenomena that are directly involved in
practically all pathologies and especially in aging. Oxidative stress, which is associated with …

Microglia‐mediated neuroinflammation is one of the most remarkable hallmarks of
neurodegenerative diseases (NDDs), including AD, PD, and ALS. Accumulating evidence …

Listeria monocytogenes is a food-borne pathogen responsible for neurolisteriosis, which is
potentially lethal in immunocompromised individuals. Microglia are the main target cells for …

Alzheimer's disease (AD) is the most frequent type of dementia. Acteoside (ACT) is a
compound isolated from Cistanche tubulosa, which possesses excellent neuroprotective …

Neurodegenerative diseases (NDs) commonly present misfolded and aggregated proteins.
Considerable research has been performed to unearth the molecular processes …

Neurodegenerative diseases (NDD) are disorders characterized by the progressive loss of
neurons affecting motor, sensory, and/or cognitive functions. The incidence of these …

Porcine Liver Decomposition Product (PLDP) was obtained by treating pig liver homogenate
with protease and filling it into capsules. We have already confirmed from three clinical trials …