Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease

K Donald, BB Finlay - Nature Reviews Immunology, 2023 - nature.com
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …

The association between early-life gut microbiota and long-term health and diseases

A Sarkar, JY Yoo, S Valeria Ozorio Dutra… - Journal of clinical …, 2021 - mdpi.com
Early life gut microbiota have been increasingly recognized as major contributors to short
and/or long-term human health and diseases. Numerous studies have demonstrated that …

Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants

J Samara, S Moossavi, B Alshaikh, VA Ortega… - Cell host & …, 2022 - cell.com
Probiotics are increasingly administered to premature infants to prevent necrotizing
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …

The sporobiota of the human gut

M Egan, E Dempsey, CA Ryan, RP Ross, C Stanton - Gut microbes, 2021 - Taylor & Francis
The human gut microbiome is a diverse and complex ecosystem that plays a critical role in
health and disease. The composition of the gut microbiome has been well studied across all …

Deterministic transition of enterotypes shapes the infant gut microbiome at an early age

L Xiao, J Wang, J Zheng, X Li, F Zhao - Genome biology, 2021 - Springer
Background The succession of the gut microbiota during the first few years plays a vital role
in human development. We elucidate the characteristics and alternations of the infant gut …

Maternal exposures and the infant gut microbiome: a systematic review with meta-analysis

A Grech, CE Collins, A Holmes, R Lal, K Duncanson… - Gut …, 2021 - Taylor & Francis
Early life, including the establishment of the intestinal microbiome, represents a critical
window of growth and development. Postnatal factors affecting the microbiome, including …

Annual Research Review: Critical windows–the microbiota–gut–brain axis in neurocognitive development

CSM Cowan, TG Dinan, JF Cryan - Journal of Child …, 2020 - Wiley Online Library
The gut microbiota is a vast, complex, and fascinating ecosystem of microorganisms that
resides in the human gastrointestinal tract. As an integral part of the microbiota–gut–brain …

The role of human milk oligosaccharides and probiotics on the neonatal microbiome and risk of necrotizing enterocolitis: a narrative review

LS Nolan, JM Rimer, M Good - Nutrients, 2020 - mdpi.com
Preterm infants are a vulnerable population at risk of intestinal dysbiosis. The newborn
microbiome is dominated by Bifidobacterium species, though abnormal microbial …

Human gut microbiota plasticity throughout the life course

K Thriene, KB Michels - … Journal of Environmental Research and Public …, 2023 - mdpi.com
The role of the gut microbiota in human health and disease has garnered heightened
attention over the past decade. A thorough understanding of microbial variation over the life …

Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity

KZ Sanidad, M Amir, A Ananthanarayanan… - Science …, 2022 - science.org
The gut microbiome elicits antigen-specific immunoglobulin G (IgG) at steady state that cross-
reacts to pathogens to confer protection against systemic infection. The role of gut …