Hippo signaling pathway and respiratory diseases
W Tang, M Li, X Yangzhong, X Zhang, A Zu… - Cell Death …, 2022 - nature.com
The hippo signaling pathway is a highly conserved evolutionary signaling pathway that
plays an important role in regulating cell proliferation, organ size, tissue development, and …
plays an important role in regulating cell proliferation, organ size, tissue development, and …
Delivery systems of therapeutic nucleic acids for the treatment of acute lung injury/acute respiratory distress syndrome
C Zhuang, M Kang, M Lee - Journal of Controlled Release, 2023 - Elsevier
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a devastating
inflammatory lung disease with a high mortality rate. ALI/ARDS is induced by various …
inflammatory lung disease with a high mortality rate. ALI/ARDS is induced by various …
Paving the way for phage therapy using novel drug delivery approaches
T Briot, C Kolenda, T Ferry, M Medina, F Laurent… - Journal of Controlled …, 2022 - Elsevier
Bacterial resistance against antibiotics is an emergent medical issue. The development of
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …
novel therapeutic approaches is urgently needed and, in this context, bacteriophages …
A review of non-invasive drug delivery through respiratory routes
YB Zhang, D Xu, L Bai, YM Zhou, H Zhang, YL Cui - Pharmaceutics, 2022 - mdpi.com
With rapid and non-invasive characteristics, the respiratory route of administration has
drawn significant attention compared with the limitations of conventional routes. Respiratory …
drawn significant attention compared with the limitations of conventional routes. Respiratory …
Preventing acute lung injury from progressing to pulmonary fibrosis by maintaining ERS homeostasis through a multistage targeting nanomicelle
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) or pulmonary fibrosis (PF)
has been regarded as a global health issue with high mortality and limited drug therapy …
has been regarded as a global health issue with high mortality and limited drug therapy …
Inflammation‐modulating nanoparticles for pneumonia therapy
W Muhammad, Z Zhai, S Wang… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Pneumonia is a common but serious infectious disease, and is the sixth leading cause for
death. The foreign pathogens such as viruses, fungi, and bacteria establish an inflammation …
death. The foreign pathogens such as viruses, fungi, and bacteria establish an inflammation …
Histopathological, physiological and biochemical assessment of resveratrol nanocapsules efficacy in bleomycin-induced acute and chronic lung injury in rats
Acute lung injury (ALI) is a life-threatening illness which may progress to chronic pulmonary
fibrosis (CPF). Resveratrol (RSV), a natural polyphenol, is known to exert several …
fibrosis (CPF). Resveratrol (RSV), a natural polyphenol, is known to exert several …
High Targeting Specificity toward Pulmonary Inflammation Using Mesenchymal Stem Cell‐Hybrid Nanovehicle for an Efficient Inflammation Intervention
Y Su, T Huang, H Sun, R Lin, X Zheng… - Advanced …, 2023 - Wiley Online Library
Pulmonary inflammation is one of the most reported tissue inflammations in clinic.
Successful suppression of inflammation is vital to prevent further inevitably fatal lung …
Successful suppression of inflammation is vital to prevent further inevitably fatal lung …
Nano‐enabled reposition of proton pump inhibitors for TLR inhibition: toward a new targeted nanotherapy for acute lung injury
L Sun, Y Liu, X Liu, R Wang, J Gong… - Advanced …, 2022 - Wiley Online Library
Toll‐like receptor (TLR) activation in macrophages plays a critical role in the pathogenesis of
acute lung injury (ALI). While TLR inhibition is a promising strategy to control the …
acute lung injury (ALI). While TLR inhibition is a promising strategy to control the …
An mTOR siRNA‐Loaded Spermidine/DNA Tetrahedron Nanoplatform with a Synergistic Anti‐Inflammatory Effect on Acute Lung Injury
C Huang, Q You, J Xu, D Wu, H Chen… - Advanced …, 2022 - Wiley Online Library
Acute lung injury (ALI) is characterized by severe inflammation and damage to the lung air–
blood barrier, resulting in respiratory function damage and life‐threatening outcomes …
blood barrier, resulting in respiratory function damage and life‐threatening outcomes …