Background: Normal brain development, mood, and cognitive functions depend on thyroid
hormone (TH) action. However, little is known about how TH mediates its actions in the …

Context Hypothyroidism is often associated with cognitive and emotional dysregulation;
however, the underlying neuropathological mechanisms remain elusive. Objective The …

Euthyroidism can be postulated to be comprised of biochemical euthyroidism and clinical
euthyroidism [1]. It would naturally be anticipated that these states would generally coexist …

Background The past decade has witnessed a surge of articles describing the
neurocognitive sequelae and associated structural and functional brain abnormalities of …

Background Magnetic resonance imaging (MRI) brain abnormalities have been reported in
the corpus callosum (CC) of patients with adult-onset hypothyroidism. However, no study …

Adult-onset hypothyroidism impairs normal brain function. Research on animal models of
hypothyroidism has revealed critical information on how deficiency of thyroid hormones …

With the advent of advanced MRI technology to study the impact of non-neurological
diseases on the brain, thyroidologists worldwide have sought to identify the structural and …

Purpose Abnormal spontaneous neuronal activities associated with cognitive deficits and
emotional dysfunction were found in hypothyroidism. However, routine method employs a …