Non FDG PET

C Nanni, L Fantini, S Nicolini, S Fanti - Clinical radiology, 2010 - Elsevier
2-[18F]-fluoro-2-deoxy-d-glucose (FDG) is the radiopharmaceutical most frequently used for
clinical positron emission tomography (PET). However, FDG cannot be used for many …

[18F] Fluoroalkyl agents: synthesis, reactivity and application for development of PET ligands in molecular imaging

MR Zhang, K Suzuki - Current Topics in Medicinal Chemistry, 2007 - ingentaconnect.com
Fluorine-18 (18F, β+; 96.7%, T1/2= 109.8 min) is of considerable importance for developing
positron emission tomography (PET) ligands for imaging receptor, enzyme, gene expression …

PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements

SS Zoghbi, HU Shetty, M Ichise, M Fujita… - Journal of Nuclear …, 2006 - Soc Nuclear Med
18F-2β-Carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl) nortropane (18F-FECNT), a
PET radioligand for the dopamine transporter (DAT), generates a radiometabolite that enters …

Direct comparison of FP-CIT SPECT and F-DOPA PET in patients with Parkinson's disease and healthy controls

SA Eshuis, PL Jager, RP Maguire, S Jonkman… - European journal of …, 2009 - Springer
Abstract Purpose Diagnosing Parkinson's disease (PD) on clinical grounds may be difficult,
especially in the early stages of the disease. F-DOPA PET and FP-CIT SPECT scans are …

Comparison of FP-CIT SPECT with F-DOPA PET in patients with de novo and advanced Parkinson's disease

SA Eshuis, RP Maguire, KL Leenders… - European journal of …, 2006 - Springer
Abstract Purpose Diagnosis of Parkinson's disease (PD) can be difficult. F-DOPA PET is
able to quantify striatal dopa decarboxylase activity and storage capacity of F-dopamine, but …

18F-labeled FECNT: a selective radioligand for PET imaging of brain dopamine transporters

MM Goodman, CD Kilts, R Keil, B Shi… - Nuclear medicine and …, 2000 - Elsevier
Fluorine-18 labeled 2β-carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl) nortropane
(FECNT) was synthesized in the development of a dopamine transporter (DAT) imaging …

Initial human PET imaging studies with the dopamine transporter ligand 18F-FECNT

MR Davis, JR Votaw, JD Bremner… - Journal of Nuclear …, 2003 - Soc Nuclear Med
The aim of this study was to do an initial assessment of the usefulness of 2β-carbomethoxy-
3β-(4-chlorophenyl)-8-(2-18F-fluoroethyl) nortropane (18F-FECNT) PET scanning in …

One-step high-radiochemical-yield synthesis of [18F] FP-CIT using a protic solvent system

SJ Lee, SJ Oh, DY Chi, SH Kang, HS Kil, JS Kim… - Nuclear medicine and …, 2007 - Elsevier
Although [18F] fluoropropylcarbomethoxyiodophenylnortro… (FP-CIT) is a promising
radiopharmaceutical for dopamine transporter imaging, it has not been used for clinical …

18F-DOPA PET and PET/CT

C Nanni, S Fanti, D Rubello - Journal of Nuclear Medicine, 2007 - Soc Nuclear Med
In the study of Timmers et al.(1) published in this issue of The Journal of Nuclear Medicine,
11 patients with pheochromocytoma and extraadrenal abdominal paraganglioma were …

Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I

HU Shetty, SS Zoghbi, JS Liow, M Ichise… - European journal of …, 2007 - Springer
Purpose We aimed to determine the composition of radioactivity in rat brain after intravenous
administration of the dopamine transporter radioligand,[11 C] PE2I. Methods PET time …