[HTML][HTML] Microglia: The breakthrough to treat neovascularization and repair blood-retinal barrier in retinopathy

X Fu, S Feng, H Qin, L Yan, C Zheng… - Frontiers in Molecular …, 2023 - frontiersin.org
Microglia are the primary resident retinal macrophages that monitor neuronal activity in real-
time and facilitate angiogenesis during retinal development. In certain retinal diseases, the …

Angiotensin II type-2 receptor attenuates liver fibrosis progression by suppressing IRE1α-XBP1 pathway

Y An, C Xu, W Liu, J Jiang, P Ye, M Yang, W Zhu, J Yu… - Cellular …, 2024 - Elsevier
The renin-angiotensin system (RAS) has been recognized as a crucial contributor to the
development of liver fibrosis, and AT2R, an essential component of RAS, is involved in the …

Activation of angiotensin II type 2 receptor attenuates lung injury of collagen-induced arthritis by alleviating endothelial cell injury and promoting Ly6Clo monocyte …

Q Xu, J Chen, W Ye, C Zhang, D Wang, W Wei… - European Journal of …, 2023 - Elsevier
As one of the most frequent extra-articular manifestations of rheumatoid arthritis (RA),
interstitial lung disease (ILD) is still challenging due to unrevealed pathophysiological …

Bone-Targeted Delivery of Novokinin, an Angiotensin II Type 2 Receptor Agonist, for Improved Pharmacokinetics and Therapeutic Effects

A Ranjit - 2023 - search.proquest.com
The renin-angiotensin system (RAS) is an intricate endocrine cascade that elicits diverse
biological functions. Angiotensin II (Ang II), as a central component of the RAS, mediates …