SARS-CoV-2: Targeted managements and vaccine development

M Bakhiet, S Taurin - Cytokine & growth factor reviews, 2021 - Elsevier
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …

Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review

M Su, T Tang, W Tang, Y Long, L Wang… - Frontiers in …, 2023 - frontiersin.org
Diabetes is a significant chronic endocrine/metabolism disorder that can result in a number
of life-threatening consequences. According to research, the gut microbiota is strongly linked …

[HTML][HTML] Type 1 diabetes and engineering enhanced islet transplantation

A Jeyagaran, C Lu, A Zbinden, AL Birkenfeld… - Advanced drug delivery …, 2022 - Elsevier
The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …

Phagosome maturation in macrophages: Eat, digest, adapt, and repeat

A Fountain, S Inpanathan, P Alves… - Advances in Biological …, 2021 - Elsevier
Phagocytosis is a dynamic process that requires an intricate interplay between phagocytic
receptors, membrane lipids, and numerous signalling proteins and their effectors, to …

Microbiota–host interactions shape ageing dynamics

M Popkes, DR Valenzano - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Occupying the interface between host and environment, host-associated microbes play
fundamental roles in nutrient absorption, essential metabolite synthesis, development of the …

Engineering surface patterns on nanoparticles: new insights into nano-bio interactions

B Hu, R Liu, Q Liu, Y Shi, J Li, L Wang, L Li… - Journal of Materials …, 2022 - pubs.rsc.org
The surface properties of nanoparticles affect their fate in biological systems. Based on
nanotechnology and its methodology, pioneering studies have explored the effects of …

Innate immunity: a balance between disease and adaption to stress

I Faenza, WL Blalock - Biomolecules, 2022 - mdpi.com
Since first being documented in ancient times, the relation of inflammation with injury and
disease has evolved in complexity and causality. Early observations supported a cause …

Idiosyncratic biogenesis of intracellular pathogens-containing vacuoles

B Vaughn, Y Abu Kwaik - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
While most bacterial species taken up by macrophages are degraded through processing of
the bacteria-containing vacuole through the endosomal-lysosomal degradation pathway …

The role of cytokines and chemokines in the inflammatory response

G Harvanová, S Duranková… - Alergologia Polska-Polish …, 2023 - termedia.pl
All organisms are interconnected through the processes and relationships that take place
within them. It is the interdependence of organs that forms the overall complex. In the course …

Innate immune receptor clustering and its role in immune regulation

M Li, Y Yu - Journal of Cell Science, 2021 - journals.biologists.com
The discovery of receptor clustering in the activation of adaptive immune cells has
revolutionized our understanding of the physical basis of immune signal transduction. In …