Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Design of superior phototheranostic agents guided by Jablonski diagrams

G Feng, GQ Zhang, D Ding - Chemical Society Reviews, 2020 - pubs.rsc.org
Phototheranostics represents a promising direction for modern precision medicine, which
has recently attracted great research interest from multidisciplinary research areas. Organic …

Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles

J Li, Y Luo, Z Zeng, D Cui, J Huang, C Xu, L Li… - Nature …, 2022 - nature.com
Nanomedicine holds promise to enhance cancer immunotherapy; however, its potential to
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …

Chemiluminescence for bioimaging and therapeutics: recent advances and challenges

M Yang, J Huang, J Fan, J Du, K Pu… - Chemical Society Reviews, 2020 - pubs.rsc.org
Chemiluminescence, the generation of light through chemiexcitation as a result of chemical
reactions, has emerged as a novel tool for bioimaging and therapy in vivo. Due to the …

Room‐temperature phosphorescence resonance energy transfer for construction of near‐infrared afterglow imaging agents

Q Dang, Y Jiang, J Wang, J Wang, Q Zhang… - Advanced …, 2020 - Wiley Online Library
Afterglow imaging that detects photons after cessation of optical excitation avoids tissue
autofluorescence and thus possesses higher sensitivity than traditional fluorescence …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

Activatable molecular probes for second near‐infrared fluorescence, chemiluminescence, and photoacoustic imaging

J Huang, K Pu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
Optical imaging plays a crucial role in biomedicine. However, due to strong light scattering
and autofluorescence in biological tissue between 650–900 nm, conventional optical …

Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation

J Li, K Pu - Chemical Society Reviews, 2019 - pubs.rsc.org
Biophotonics as a highly interdisciplinary frontier often requires the assistance of optical
agents to control the light pathways in cells, tissues and living organisms for specific …

Amplification of activated near-infrared afterglow luminescence by introducing twisted molecular geometry for understanding neutrophil-involved diseases

C Chen, H Gao, H Ou, RTK Kwok, Y Tang… - Journal of the …, 2022 - ACS Publications
Understanding the mechanism and progression of neutrophil-involved diseases (eg, acute
inflammation) is of great importance. However, current available analytical methods neither …

Supramolecular assembly confined purely organic room temperature phosphorescence and its biological imaging

WL Zhou, W Lin, Y Chen, Y Liu - Chemical Science, 2022 - pubs.rsc.org
Purely organic room temperature phosphorescence, especially in aqueous solution, is
attracting increasing attention owing to its large Stokes shift, long lifetime, low preparation …