[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …
Burden of pancreatic cancer: from epidemiology to practice
N Khalaf, HB El-Serag, HR Abrams, AP Thrift - Clinical Gastroenterology …, 2021 - Elsevier
Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide with
432,242 related deaths in 2018. Unlike other cancers, the incidence of pancreatic cancer …
432,242 related deaths in 2018. Unlike other cancers, the incidence of pancreatic cancer …
Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA
GD Guler, Y Ning, CJ Ku, T Phillips, E McCarthy… - Nature …, 2020 - nature.com
Pancreatic cancer is often detected late, when curative therapies are no longer possible.
Here, we present non-invasive detection of pancreatic ductal adenocarcinoma (PDAC) by 5 …
Here, we present non-invasive detection of pancreatic ductal adenocarcinoma (PDAC) by 5 …
Early detection of pancreatic cancer using DNA-based molecular approaches
Due to its poor prognosis and the late stage at which it is typically diagnosed, early detection
of pancreatic cancer is a pressing clinical problem. Advances in genomic analysis of human …
of pancreatic cancer is a pressing clinical problem. Advances in genomic analysis of human …
Prospective, multi-institutional, real-time next-generation sequencing of pancreatic cyst fluid reveals diverse genomic alterations that improve the clinical management …
A Paniccia, PM Polanco, BA Boone, AI Wald… - Gastroenterology, 2023 - Elsevier
Background & Aims Next-generation sequencing (NGS) of pancreatic cyst fluid is a useful
adjunct in the assessment of patients with pancreatic cyst. However, previous studies have …
adjunct in the assessment of patients with pancreatic cyst. However, previous studies have …
[HTML][HTML] Biomarkers in the diagnosis of pancreatic cancer: Are we closer to finding the golden ticket?
RS O'Neill, A Stoita - World journal of gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …
A multimodality test to guide the management of patients with a pancreatic cyst
Pancreatic cysts are common and often pose a management dilemma, because some cysts
are precancerous, whereas others have little risk of developing into invasive cancers. We …
are precancerous, whereas others have little risk of developing into invasive cancers. We …
Pancreatic cancer: changing epidemiology and new approaches to risk assessment, early detection, and prevention
EM Stoffel, RE Brand, M Goggins - Gastroenterology, 2023 - Elsevier
Pancreatic cancer usually results in poor survival with limited options for treatment, as most
affected individuals present with advanced disease. Early detection of preinvasive …
affected individuals present with advanced disease. Early detection of preinvasive …
Radiomics in stratification of pancreatic cystic lesions: Machine learning in action
Pancreatic cystic lesions (PCLs) are well-known precursors of pancreatic cancer. Their
diagnosis can be challenging as their behavior varies from benign to malignant disease …
diagnosis can be challenging as their behavior varies from benign to malignant disease …
Pancreatic cystic lesions and malignancy: assessment, guidelines, and the field defect
FH Miller, C Lopes Vendrami, HS Recht, CG Wood… - Radiographics, 2022 - pubs.rsna.org
The widespread use of high–spatial-resolution cross-sectional imaging has led to an
increase in detection of incidental pancreatic cystic lesions. These lesions are a diverse …
increase in detection of incidental pancreatic cystic lesions. These lesions are a diverse …