[HTML][HTML] Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients
RP Veiga, JA Paiva - Critical Care, 2018 - Springer
Antimicrobials are among the most important and commonly prescribed drugs in the
management of critically ill patients and beta-lactams are the most common antibiotic class …
management of critically ill patients and beta-lactams are the most common antibiotic class …
Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: a systematic review and meta …
ME Falagas, GS Tansarli, K Ikawa… - Clinical infectious …, 2013 - academic.oup.com
We sought to study whether the better pharmacokinetic and pharmacodynamic (PK/PD)
properties of carbapenems and piperacillin/tazobactam, when the duration of infusion is …
properties of carbapenems and piperacillin/tazobactam, when the duration of infusion is …
[HTML][HTML] Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016
A Rhodes, LE Evans, W Alhazzani, MM Levy… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …
[PDF][PDF] S3-leitlinie sepsis–prävention, diagnose, therapie und nachsorge
FM Brunkhorst, MA Weigand, M Pletz… - 2020 - publications.goettingen-research …
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …
Continuous infusion of beta-lactam antibiotics: Narrative review of systematic reviews, and implications for outpatient parenteral antibiotic therapy
JA Roberts, K Croom, N Adomakoh - Expert Review of Anti-infective …, 2023 - Taylor & Francis
Introduction Continuous infusion (CI) of beta-lactam antibiotics may be of benefit in some
patients, particularly those with severe infections. However, most studies have been small …
patients, particularly those with severe infections. However, most studies have been small …
[HTML][HTML] S3 Guideline Sepsis—prevention, diagnosis, therapy, and aftercare: long version
FM Brunkhorst, MA Weigand, M Pletz… - Medizinische Klinik …, 2020 - Springer
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …
[HTML][HTML] Clinical outcomes with alternative dosing strategies for piperacillin/tazobactam: a systematic review and meta-analysis
H Yang, C Zhang, Q Zhou, Y Wang, L Chen - PloS one, 2015 - journals.plos.org
Objectives A better dosing strategy can improve clinical outcomes for patients. We sought to
compare the extended or continuous infusion with conventional intermittent infusion of …
compare the extended or continuous infusion with conventional intermittent infusion of …
Continuous and prolonged intravenous β-lactam dosing: implications for the clinical laboratory
M Grupper, JL Kuti, DP Nicolau - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Beta-lactam antibiotics serve as a cornerstone in the management of bacterial infections
because of their wide spectrum of activity and low toxicity. Since resistance rates among …
because of their wide spectrum of activity and low toxicity. Since resistance rates among …
[HTML][HTML] Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: An overview of systematic reviews
Objective This overview of reviews aims to map and compare of objectives, methods, and
findings of existing systematic reviews to develop a greater understanding of the information …
findings of existing systematic reviews to develop a greater understanding of the information …
[HTML][HTML] Clinical outcomes of extended versus intermittent administration of piperacillin/tazobactam for the treatment of hospital-acquired pneumonia: a randomized …
The purpose of this study was to assess the pharmacokinetic (PK) characteristics, clinical
efficiency, and pharmacoeconomic parameters of piperacillin/tazobactam administered by …
efficiency, and pharmacoeconomic parameters of piperacillin/tazobactam administered by …