Big data in transfusion medicine and artificial intelligence analysis for red blood cell quality control

MGM Lopes, SM Recktenwald, G Simionato… - Transfusion Medicine …, 2023 - karger.com
Background:“Artificial intelligence” and “big data” increasingly take the step from just being
interesting concepts to being relevant or even part of our lives. This general statement holds …

[HTML][HTML] Structural and mechanical properties of the red blood cell's cytoplasmic membrane seen through the lens of biophysics

S Himbert, MC Rheinstädter - Frontiers in Physiology, 2022 - frontiersin.org
Red blood cells (RBCs) are the most abundant cell type in the human body and critical
suppliers of oxygen. The cells are characterized by a simple structure with no internal …

Label-free and noninvasive single-cell characterization for the viscoelastic properties of cryopreserved human red blood cells using a dielectrophoresis-on-a-chip …

Q Hu, Z Wang, L Shen, G Zhao - Analytical Chemistry, 2022 - ACS Publications
Successful human red blood cell cryopreservation techniques have been gradually
developed in recent decades, with great potential for use in clinical medicine and basic …

In vivo optical trapping of erythrocytes in mouse liver imaged with oblique back-illumination microscopy

M Shao, R Liu, C Li, Z Chai, Z Zhong, F Lu… - Applied Physics …, 2023 - pubs.aip.org
Optical tweezers are ideal tools for cell manipulation in vivo due to their non-contact trapping
ability. In the current studies, the optical trapping of cells can only be achieved in light …

Extensional-flow impedance cytometer for contactless and optics-free erythrocyte deformability analysis

R Reale, A De Ninno, T Nepi… - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Objective: Deformability is an essential feature of red blood cells (RBCs), enabling them to
undergo significant shape change in response to external forces. Impaired erythrocyte …

Intelligent image-based deformability assessment of red blood cells via dynamic shape classification

M Liang, J Zhong, CS Shannon, R Agrawal… - Sensors and Actuators B …, 2024 - Elsevier
Red blood cells (RBC), the primary component of whole blood, play an essential role in
maintaining blood fluidity and mass transport throughout the human body. RBC …

Cells in the polyaneuploid cancer cell (PACC) state have increased metastatic potential

MM Mallin, N Kim, MI Choudhury, SJ Lee… - Clinical & Experimental …, 2023 - Springer
Although metastasis is the leading cause of cancer deaths, it is quite rare at the cellular
level. Only a rare subset of cancer cells (~ 1 in 1.5 billion) can complete the entire metastatic …

Effect of cell age and membrane rigidity on red blood cell shape in capillary flow

M Nouaman, A Darras, T John, G Simionato, MAE Rab… - Cells, 2023 - mdpi.com
Blood flow in the microcirculatory system is crucially affected by intrinsic red blood cell
(RBC) properties, such as their deformability. In the smallest vessels of this network, RBCs …

[HTML][HTML] Confinement effect on the microcapillary flow and shape of red blood cells

M Nouaman, A Darras, C Wagner, SM Recktenwald - Biomicrofluidics, 2024 - pubs.aip.org
The ability to change shape is essential for the proper functioning of red blood cells (RBCs)
within the microvasculature. The shape of RBCs significantly influences blood flow and has …

Machine Learning Microfluidic based platform: Integration of Lab-on-Chip devices and data analysis algorithms for Red Blood Cell plasticity evaluation in Pyruvate …

A Mencattini, V Rizzuto, G Antonelli… - Sensors and Actuators A …, 2023 - Elsevier
Microfluidics represents a very promising technological solution for conducting massive
biological experiments. However, the difficulty of managing the amount of information …