It is important to develop new insecticides with a new mode of action because of increasing
pesticide resistance. In this study, a series of novel aryl isoxazoline derivatives containing …

The discovery of novel and easily available leads provides a convincing solution to
agrochemical innovation. A bioassay-guided scaffold subtraction of the previous “Chem-Bio …

To promote the development of novel agricultural succinate dehydrogenase inhibitor (SDHI)
fungicides, we introduced cinnamamide and nicotinamide structural fragments into the …

Succinate dehydrogenase (SDH, EC 1.3. 5.1, also known as complex II) has been
recognized as one of the most promising targets of fungicides. Here, based on the binding …

In an effort to promote the development of new fungicides, a series of 48 novel N-(1-methyl-4-
thiocyanato-1 H-pyrazol-5-yl)-benzamide derivatives A1–A36 and B1–B12 were designed …

Scaffold hopping strategy has become one of the most successful methods in the process of
molecular design. Seeking to develop novel succinate dehydrogenase inhibitors (SDHIs) …

4-Hydroxyphenylpyruvate dioxygenase (HPPD) is a crucial target enzyme in albino
herbicides. The inhibition of HPPD activity interferes with the synthesis of carotenoids …

With fungal diseases posing a major threat to agricultural production, the application of
fungicides to control related diseases is often considered necessary to ensure the world's …

The dearomatization at the hydrophobic tail of the boscalid was carried out to construct a
series of novel pyrazole-4-carboxamide derivatives containing an oxime ether fragment. By …

The development of new fungicide molecules is a crucial task for agricultural chemists to
enhance the effectiveness of fungicides in agricultural production. In this study, a series of …