Regulation of progesterone receptor expression in endometriosis, endometrial cancer, and breast cancer by estrogen, polymorphisms, transcription factors, epigenetic …
H Pu, X Wen, DX Luo, Z Guo - The Journal of Steroid Biochemistry and …, 2023 - Elsevier
The uterus and breasts are hormone-responsive tissues. Progesterone and estradiol
regulate gonadotropin secretion, prepare the endometrium for implantation, maintain …
regulate gonadotropin secretion, prepare the endometrium for implantation, maintain …
Recent advances in gold and silver nanoparticle based therapies for lung and breast cancers
P Malik, TK Mukherjee - International Journal of Pharmaceutics, 2018 - Elsevier
In recent years, gold (Au) and silver (Ag) nanoparticles (NPs) have been the centerstage of
improving cancer treatments and therapies, substantially attributed to their size and shape …
improving cancer treatments and therapies, substantially attributed to their size and shape …
The role of progesterone and the progesterone receptor in cancer: progress in the last 5 years
JH Check, DL Check - Expert Review of Endocrinology & …, 2023 - Taylor & Francis
Introduction Patients with various advanced cancers devoid of nuclear progesterone
receptors (nPR) have demonstrated increased quality and length of life when treated with …
receptors (nPR) have demonstrated increased quality and length of life when treated with …
Lung cancer–standard therapy and the use of a novel, highly effective, well tolerated, treatment with progesterone receptor modulators
JH Check, T Poretta, D Check… - Anticancer Research, 2023 - ar.iiarjournals.org
The most recent successful advances in lung cancer therapy have directly and increasingly
focused on personalized tumor genetic/epigenetic/immunologic profiling, and the …
focused on personalized tumor genetic/epigenetic/immunologic profiling, and the …
Mifepristone extends both length and quality of life in a patient with advanced non-small cell lung cancer that has progressed despite chemotherapy and a check-point …
JH Check, D Check, T Poretta - Anticancer Research, 2019 - ar.iiarjournals.org
Case Report: Case 1 of an investigator-initiated study using oral single agent mifepristone to
halt stage IV non-small cell lung cancer whose tumor was devoid of any targeted markers …
halt stage IV non-small cell lung cancer whose tumor was devoid of any targeted markers …
Therapy aimed to suppress the production of the immunosuppressive protein progesterone induced blocking factor (PIBF) may provide palliation and/or increased …
JH Check, D Check - Anticancer Research, 2019 - ar.iiarjournals.org
Progesterone induced blocking factor (PIBF) is a unique protein that is not present in normal
cells, but is found predominantly in rapidly growing cells of the fetal placental unit or cancer …
cells, but is found predominantly in rapidly growing cells of the fetal placental unit or cancer …
[HTML][HTML] Gene networks and transcriptional regulators associated with liver cancer development and progression
T Meier, M Timm, M Montani, L Wilkens - BMC Medical Genomics, 2021 - Springer
Background Treatment options for hepatocellular carcinoma (HCC) are limited, and overall
survival is poor. Despite the high frequency of this malignoma, its basic disease …
survival is poor. Despite the high frequency of this malignoma, its basic disease …
[HTML][HTML] DeepSnap-deep learning approach predicts progesterone receptor antagonist activity with high performance
Y Matsuzaka, Y Uesawa - Frontiers in bioengineering and …, 2020 - frontiersin.org
The progesterone receptor (PR) is important therapeutic target for many malignancies and
endocrine disorders due to its role in controlling ovulation and pregnancy via the …
endocrine disorders due to its role in controlling ovulation and pregnancy via the …
In vitro antitumor activity of progesterone in human adrenocortical carcinoma
M Fragni, C Fiorentini, E Rossini, S Fisogni, S Vezzoli… - Endocrine, 2019 - Springer
Purpose The management of patients with adrenocortical carcinoma (ACC) is challenging.
As mitotane and chemotherapy show limited efficacy, there is an urgent need to develop …
As mitotane and chemotherapy show limited efficacy, there is an urgent need to develop …
[HTML][HTML] A hypothetical model suggesting some possible ways that the progesterone receptor may be involved in cancer proliferation
JH Check, DL Check - International Journal of Molecular Sciences, 2021 - mdpi.com
Cancer and the fetal-placental semi-allograft share certain characteristics, eg, rapid
proliferation, the capacity to invade normal tissue, and, related to the presence of antigens …
proliferation, the capacity to invade normal tissue, and, related to the presence of antigens …