Colonization and Infection of Indwelling Medical Devices by Staphylococcus aureus with an Emphasis on Orthopedic Implants

G Pietrocola, D Campoccia, C Motta… - International journal of …, 2022 - mdpi.com
The use of indwelling medical devices has constantly increased in recent years and has
revolutionized the quality of life of patients affected by different diseases. However, despite …

Transformable ECM deprivation system effectively suppresses renal cell carcinoma by reversing anoikis resistance and increasing chemotherapy sensitivity

L Wang, C Li, J Wang, G Yang, Y Lv, B Fu… - Advanced …, 2022 - Wiley Online Library
Extracellular matrix (ECM) is crucial in various biological functions during tumor progression,
including induction of anoikis resistance and cell adhesion‐mediated drug resistance (CAM …

The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections

M Bhattacharya, AR Horswill - FEMS Microbiology Reviews, 2024 - academic.oup.com
Twenty to forty one percent of the world's population is either transiently or permanently
colonized by the Gram-positive bacterium, Staphylococcus aureus. In 2017, the CDC …

FN1 is a prognostic biomarker and correlated with immune infiltrates in gastric cancers

H Wang, J Zhang, H Li, H Yu, S Chen, S Liu… - Frontiers in …, 2022 - frontiersin.org
Fibronectin 1 (FN1) is a glycoprotein found throughout the extracellular matrix that has a role
in the onset and progression of cancer. However, its immune relationship with gastric cancer …

An immunoinformatics and structural vaccinology study to design a multi‐epitope vaccine against Staphylococcus aureus infection

R Chatterjee, SR Mahapatra, J Dey… - Journal of Molecular …, 2023 - Wiley Online Library
Staphylococcus aureus has been widely reported to be majorly responsible for causing
nosocomial infections worldwide. Due to an increase in antibiotic‐resistant strains, the …

Group A streptococci induce stronger M protein-fibronectin interaction when specific human antibodies are bound

S Wrighton, VK Ahnlide, O André, W Bahnan… - Frontiers in …, 2023 - frontiersin.org
Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to
manipulate the immune system through various mechanisms. GAS'M protein constitutes a …

NADH oxidase of Mycoplasma synoviae is a potential diagnostic antigen, plasminogen/fibronectin binding protein and a putative adhesin

Z Hu, H Li, Y Zhao, G Wang, Y Shang, Y Chen… - BMC Veterinary …, 2022 - Springer
Background Mycoplasma synoviae (MS) is an important pathogen causing respiratory
diseases and arthritis in chickens and turkeys, thus, resulting in serious economic losses to …

Screening of the key genes and signalling pathways for diabetic nephropathy using bioinformatics analysis

Z Li, J Feng, J Zhong, M Lu, X Gao… - Frontiers in …, 2022 - frontiersin.org
Background This study aimed to identify biological markers for diabetic nephropathy (DN)
and explore their underlying mechanisms. Methods Four datasets, GSE30528, GSE47183 …

Monoclonal antibodies targeting surface-exposed and secreted proteins from staphylococci

P Speziale, G Pietrocola - Vaccines, 2021 - mdpi.com
Staphylococci (specifically Staphylococcus aureus and Staphylococcus epidermidis) are the
causative agents of diseases ranging from superficial skin and soft tissue infections to …

The protective role of exosome-derived microRNAs and proteins from human breast milk against infectious agents

KU Kim, K Han, J Kim, DH Kwon, YW Ji, DY Yi, H Min - Metabolites, 2023 - mdpi.com
Human breast milk (HBM)-derived exosomes contain various biological and immunological
components. However, comprehensive immune-related and antimicrobial factor analysis …