Host–pathogen interactions reflect the balance of host defenses and pathogen virulence
mechanisms. Advances in proteomic technologies now afford opportunities to compare …

By providing useful tools to study host–pathogen interactions, next-generation omics has
recently enabled the study of gene expression changes in both pathogen and infected host …

The Yersinia pestis proteome was studied as a function of temperature and calcium by two-
dimensional differential gel electrophoresis. Over 4,100 individual protein spots were …

Quantifying the variation in the human plasma proteome is an essential prerequisite for
disease‐specific biomarker detection. We report here on the longitudinal and individual …

В обзоре обобщены и проанализированы современные литературные данные о
способности клеток, реализующих механизмы врожденного иммунитета …

Omics has remarkably changed the way we investigate and understand life. Omics differs
from traditional hypothesis-driven research because it is a discovery-driven approach. Mass …

Yersinia pestis, the causative agent of plague, is proved to be a recently emerged clone from
Y. pseudotuberculosis. However, the diseases they cause and their patterns of transmission …

Yersinia pestis is one of the most threatening biological agents due to the associated high
mortality and history of plague pandemics. Identifying molecular players in the host …

Background Rapid detection and therapeutic intervention for infectious and emerging
diseases is a major scientific goal in biodefense and public health. Toward this end, cytokine …

Introduction Pneumonic plague is caused by the aerosolized form of Yersinia pestis and is a
highly virulent infection with complex clinical consequences, and without treatment, the …