OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Early-onset neonatal sepsis in low-and middle-income countries: current challenges and future opportunities

K Sands, OB Spiller, K Thomson… - Infection and drug …, 2022 - Taylor & Francis
Neonatal sepsis is defined as a systemic infection within the first 28 days of life, with early-
onset sepsis (EOS) occurring within the first 72h, although the definition of EOS varies in …

Neonatal Sepsis: The Impact of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae

S Mukherjee, S Mitra, S Dutta, S Basu - Frontiers in Medicine, 2021 - frontiersin.org
The convergence of a vulnerable population and a notorious pathogen is devastating, as
seen in the case of sepsis occurring during the first 28 days of life (neonatal period). Sepsis …

The crisis of carbapenemase-mediated carbapenem resistance across the human–animal–environmental interface in India

S Das - Infectious Diseases Now, 2023 - Elsevier
Carbapenems are the decision-making antimicrobials used to combat severe Gram-
negative bacterial infections in humans. Carbapenem resistance poses a potential public …

Prevalence and clonal diversity of carbapenem-resistant Klebsiella pneumoniae causing neonatal infections: A systematic review of 128 articles across 30 countries

Y Hu, Y Yang, Y Feng, Q Fang, C Wang, F Zhao… - PLoS …, 2023 - journals.plos.org
Background Klebsiella pneumoniae is the most common pathogen causing neonatal
infections, leading to high mortality worldwide. Along with increasing antimicrobial use in …

Carbapenem-resistant Klebsiella pneumoniae: the role of plasmids in emergence, dissemination, and evolution of a major clinical challenge

V Di Pilato, S Pollini, V Miriagou… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction Klebsiella pneumoniae is a major agent of healthcare-associated infections and
a cause of some community-acquired infections, including severe bacteremic infections …

Third generation cephalosporin-resistant Klebsiella pneumoniae thriving in patients and in wastewater: what do they have in common?

J Rocha, C Ferreira, D Mil-Homens, A Busquets… - BMC genomics, 2022 - Springer
Background Klebsiella pneumoniae are ubiquitous bacteria and recognized multidrug-
resistant opportunistic pathogens that can be released into the environment, mainly through …

[PDF][PDF] Fluoroquinolone resistance determinants in carbapenem-resistant Escherichia coli isolated from urine clinical samples in Thailand

P Boueroy, P Chopjitt, R Hatrongjit, M Morita… - PeerJ, 2023 - peerj.com
Background. Escherichia coli is the most common cause of urinary tract infections and has
fluoroquinolone (FQ)-resistant strains, which are a worldwide concern. Objectives. To …

[HTML][HTML] Prediction of antimicrobial minimal inhibitory concentrations for Neisseria gonorrhoeae using machine learning models

M Yasir, AM Karim, SK Malik, AA Bajaffer… - Saudi Journal of …, 2022 - Elsevier
The lowest concentration of an antimicrobial agent that can inhibit the visible growth of a
microorganism after overnight incubation is called as minimum inhibitory concentration …

Multidrug-resistant Enterobacterales responsible for septicaemia in a neonatal intensive care unit in Morocco

P Perez-Palacios, D Girlich, N Soraa, A Lamrani… - Journal of global …, 2023 - Elsevier
Objectives Neonatal sepsis caused by multidrug-resistant (MDR) bacteria has a high
morbidity and mortality, especially in low-and middle-income countries. Here, the molecular …