Rationale: Obstructive sleep apnea (OSA) has been postulated to contribute to idiopathic
pulmonary fibrosis by promoting alveolar epithelial injury via tractional forces and …

Background Clustering key clinical characteristics of participants in the Severe Asthma
Research Program (SARP), a large, multicenter prospective observational study of patients …

Lung cancer, chronic obstructive pulmonary disease, and cardiovascular disease are highly
prevalent in the general population and expected to cause most deaths by 2050. For these …

It is increasingly acknowledged that delays in the diagnosis of chronic inflammatory lung
conditions have hampered our understanding of pathogenesis and thus our ability to design …

Lung imaging is increasingly being used to diagnose, quantify, and phenotype chronic
obstructive pulmonary disease (COPD). Although spirometry is the gold standard for the …

Background CT attenuation is affected by lung volume, dosage, and scanner bias, leading to
inaccurate emphysema progression measurements in multicenter studies. Purpose To …

Rationale Individual socioeconomic status has been shown to influence the outcomes of
patients with chronic obstructive pulmonary disease (COPD). However, contextual factors …

Background Treatment and preventative advances for chronic obstructive pulmonary
disease (COPD) have been slow due, in part, to limited subphenotypes. We tested if …

Background Evaluation of impaired left ventricular (LV) filling has focused on intrinsic
causes of LV dysfunction; however, pulmonary vascular changes may contribute to reduced …

Quantitative features that can currently be obtained from medical imaging do not provide a
complete picture of Chronic Obstructive Pulmonary Disease (COPD). In this paper, we …