Nutritional immunity: the battle for nutrient metals at the host–pathogen interface
CC Murdoch, EP Skaar - Nature Reviews Microbiology, 2022 - nature.com
Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …
Oxidative stress response: a critical factor affecting the ecological competitiveness of Streptococcus mutans
X Cheng, X Xu, X Zhou, J Ning - Journal of Oral Microbiology, 2024 - Taylor & Francis
Oral microecological balance is closely associated with the development of dental caries.
Oxidative stress is one of the important factors regulating the composition and structure of …
Oxidative stress is one of the important factors regulating the composition and structure of …
Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion
SG Downes, RA Owens, K Walshe, DA Fitzpatrick… - Scientific Reports, 2023 - nature.com
Overcoming antimicrobial resistance represents a formidable challenge and investigating
bacterial growth inhibition by fungal metabolites may yield new strategies. Although the …
bacterial growth inhibition by fungal metabolites may yield new strategies. Although the …
ZccE is a Novel P-type ATPase That Protects Streptococcus mutans Against Zinc Intoxication
T Ganguly, AM Peterson, M Burkholder… - Plos …, 2022 - journals.plos.org
Zinc is a trace metal that is essential to all forms of life, but that becomes toxic at high
concentrations. Because it has both antimicrobial and anti-inflammatory properties and low …
concentrations. Because it has both antimicrobial and anti-inflammatory properties and low …
The Adc regulon mediates zinc homeostasis in Streptococcus mutans
Y Pan, Y Chen, J Chen, Q Ma, T Gong… - Molecular Oral …, 2021 - Wiley Online Library
Abstract Zinc (Zn2+) is an essential divalent trace metal for living cells. Intracellular zinc
homeostasis is critical to the survival and virulence of bacteria. Thus, the frequent …
homeostasis is critical to the survival and virulence of bacteria. Thus, the frequent …
Contribution of a ZIP‐family protein to manganese uptake and infective endocarditis virulence in Streptococcus sanguinis
Streptococcus sanguinis is an important cause of infective endocarditis. In strain SK36, the
ABC‐family manganese transporter, SsaACB, is essential for virulence. We have now …
ABC‐family manganese transporter, SsaACB, is essential for virulence. We have now …
The AdcACB/AdcAII system is essential for zinc homeostasis and an important contributor of Enterococcus faecalis virulence
LN Lam, DN Brunson, JJ Molina, AL Flores-Mireles… - Virulence, 2022 - Taylor & Francis
Bacterial pathogens require a variety of micronutrients for growth, including trace metals
such as iron, manganese, and zinc (Zn). Despite their relative abundance in host …
such as iron, manganese, and zinc (Zn). Despite their relative abundance in host …
ZccE, a P‐type ATPase contributing to biofilm formation and competitiveness in Streptococcus mutans
Y Pan, J Zou, K Zhang, X Wang, Q Ma… - Molecular Oral …, 2023 - Wiley Online Library
Most living organisms require zinc for survival; however, excessive amounts of this trace
element can be toxic. Therefore, the frequent fluctuations of salivary zinc, caused by the low …
element can be toxic. Therefore, the frequent fluctuations of salivary zinc, caused by the low …
Effect of the zinc transporter ZupT on the virulence mechanisms of mesophilic Aeromonas salmonicida SRW‐OG1
J Wang, Q Li, L Huang - Animal Research and One Health, 2023 - Wiley Online Library
As a typical psychrophilic bacterial pathogen, Aeromonas salmonicida causes furunculosis
in wild and farmed freshwater and marine fish, leading to substantial economic losses in the …
in wild and farmed freshwater and marine fish, leading to substantial economic losses in the …
ZrgA contributes to zinc acquisition in Vibrio parahaemolyticus
C Zheng, J Qiu, Y Zhai, M Wei, X Zhou, X Jiao - Virulence, 2023 - Taylor & Francis
Metals are nutrients essential for almost all lifeforms. Bacteria have evolved several
mechanisms to overcome the metal restrictions imposed by the host. Vibrio …
mechanisms to overcome the metal restrictions imposed by the host. Vibrio …