[HTML][HTML] Decreased fatty acid oxidation gene expression in pre-Eclampsia according to the onset and presence of intrauterine growth restriction
A Abascal-Saiz, E Fuente-Luelmo, M Haro… - Nutrients, 2023 - mdpi.com
Mitochondrial fatty acid oxidation (FAO) is lower in placentas with pre-eclampsia. The aim of
our study was to compare the placental mRNA expression of FAO enzymes in healthy …
our study was to compare the placental mRNA expression of FAO enzymes in healthy …
[HTML][HTML] PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis
W Lai, L Yu, Y Deng - Communications Biology, 2024 - nature.com
The study aims to explore the effect of PPARγ signaling on ferroptosis and preeclampsia
(PE) development. Serum and placental tissue are collected from healthy subjects and PE …
(PE) development. Serum and placental tissue are collected from healthy subjects and PE …
[HTML][HTML] Growth-Restricted Fetuses and Offspring Reveal Adverse Sex-Specific Metabolic Responses in Preeclamptic Mice Expressing Human sFLT1
R Vogtmann, M Bao, MV Dewan, A Riedel… - International Journal of …, 2023 - mdpi.com
Fetal adaptations to harmful intrauterine environments due to pregnancy disorders such as
preeclampsia (PE) can negatively program the offspring's metabolism, resulting in long-term …
preeclampsia (PE) can negatively program the offspring's metabolism, resulting in long-term …
[HTML][HTML] LC-MS/MS based untargeted lipidomics uncovers lipid signatures of late-onset preeclampsia
Y Yang, L Wu, Y Lv, Z Miao, Y Wang, J Yan, J Li, C Li… - Biochimie, 2023 - Elsevier
The mechanisms underlying late-onset preeclampsia (LOPE) remain unknown. Metabolic
disturbances have been implicated as a primary factor in LOPE development. Lipids have …
disturbances have been implicated as a primary factor in LOPE development. Lipids have …
[HTML][HTML] Pre-pregnancy body mass index combined with peripheral blood PLGF, DCN, LDH, and UA in a risk prediction model for pre-eclampsia
Y Zhou, C Xiao, Y Yang - Frontiers in Endocrinology, 2024 - frontiersin.org
Objective This study analyzes the levels of peripheral blood placental growth factor (PLGF),
body mass index (BMI), decorin (DCN), lactate dehydrogenase (LDH), uric acid (UA), and …
body mass index (BMI), decorin (DCN), lactate dehydrogenase (LDH), uric acid (UA), and …
[HTML][HTML] Literature Review: The sFlt1/PlGF Ratio and Pregestational Maternal Comorbidities: New Risk Factors to Predict Pre-Eclampsia
NS Karpova, OP Dmitrenko, TS Budykina - International Journal of …, 2023 - mdpi.com
One of the main causes of maternal and neonatal morbidity and mortality is pre-eclampsia. It
is characterized by a high sFlt1/PlGF ratio, according to prior research. Pregestational …
is characterized by a high sFlt1/PlGF ratio, according to prior research. Pregestational …
Early Life Exposures and Offspring Health: From Animal Models to Human Studies
M Bao - 2023 - research.rug.nl
This thesis delves into the long-term health impacts of early-life adversities in offspring, from
both animal models and humans. In animal studies, maternal infections and conditions like …
both animal models and humans. In animal studies, maternal infections and conditions like …