Molecular markers and targets for colorectal cancer prevention

NB Janakiram, CV Rao - Acta Pharmacologica Sinica, 2008 - Wiley Online Library
Colorectal cancer is the third most prevalent cancer in the world. If detected at an early
stage, treatment often might lead to cure. As prevention is better than cure, epidemiological …

Ovarian neoplasms in patients with colorectal cancer: understanding the role of prophylactic oophorectomy

NN Hanna, AM Cohen - Clinical Colorectal Cancer, 2004 - Elsevier
Although the role of prophylactic oophorectomy is currently under debate and not well
defined, it is of increasing and considerable relevance, especially in premenopausal …

Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in postmenopausal women

J Gonenne, T Esfandyari, M Camilleri… - …, 2006 - Wiley Online Library
Females are disproportionately affected by constipation, which is often aggravated during
pregnancy. Bowel function also changes during the luteal phase of the menstrual cycle. The …

Associations between ERα, ERβ, and AR Genotypes and Colon and Rectal Cancer

ML Slattery, C Sweeney, M Murtaugh, KN Ma… - … Biomarkers & Prevention, 2005 - AACR
Estrogen and androgens are thought to be involved in the etiology of colorectal cancer. We
evaluate genetic variants of the estrogen receptor genes (ERα and ERβ) and the androgen …

The inhibitory effect of diarylpropionitrile, a selective agonist of estrogen receptor beta, on the growth of MC38 colon cancer line

E Motylewska, O Stasikowska, G Mełeń-Mucha - Cancer letters, 2009 - Elsevier
The protective role of estrogens in the colon carcinogenesis has been suggested for many
years and attributed mainly to estrogen receptor beta (ERβ). However, the direct effect of …

Therapeutic strategies and potential actions of female sex steroid hormones and their receptors in colon cancer based on preclinical studies

AA Mahbub - Life, 2022 - mdpi.com
Several epidemiological studies have reported that the use of female sex steroid hormones
could reduce the risk of colon cancer (CRC). This review summarizes the available data …

Prognostic role of sex steroid receptors in pancreatic adenocarcinoma

D Georgiadou, TN Sergentanis, S Sakellariou… - … -Research and Practice, 2016 - Elsevier
From the available literature, it is unclear what proportion of pancreatic adenocarcinomas
express estrogen receptors (ERα, ERβ), progesterone receptors (PR), and androgen …

雌激素受体ERβ 与大肠癌的研究进展

姚嘉 - 中国热带医学, 2012 - cqvip.com
大肠癌是临床上常见的恶性肿瘤, 近年来其发病率及死亡率在我国都呈上升趋势, 上世纪80
年代有研究证实了外源性雌激素可能参与大肠癌的发生及发展, 人们便在这一领域展开了广泛的 …

Cytosolic levels of an estrogen-induced breast cancer-associated peptide (TFF1/pS2) in colorectal cancer: clinical significance and relationship with steroid receptors

FJ Vizoso, MC Fagilde, MD Corte… - … journal of biological …, 2003 - journals.sagepub.com
Background The Trefoil Factor 1 (TFF1/pS2), a peptide consisting of 60 amino acids, is the
most abundant estrogen-induced messenger RNA in MCF-7 breast cancer cells and is also …

Экспрессия эстрогеновых рецепторов в опухолях, отличных от рака молочной железы

ТА Богуш, ЕА Дудко, АА Бёме, ЕА Богуш… - Антибиотики и …, 2009 - cyberleninka.ru
Обзор данных литературы об экспрессии разных типов эстрогеновык рецепторов (ERa
и ERβ) в опухолях, отличнык от рака молочной железы. Приведены данные о частоте …