The dynamics of cortical neuronal activity in the first minutes after spontaneous awakening in rats and mice
Abstract Study Objective: Upon awakening from sleep, a fully awake brain state is not
reestablished immediately, but the origin and physiological properties of the distinct brain …
reestablished immediately, but the origin and physiological properties of the distinct brain …
Sleeping on the wing
NC Rattenborg - Interface Focus, 2017 - royalsocietypublishing.org
Wakefulness enables animals to interface adaptively with the environment. Paradoxically, in
insects to humans, the efficacy of wakefulness depends on daily sleep, a mysterious, usually …
insects to humans, the efficacy of wakefulness depends on daily sleep, a mysterious, usually …
Optogenetic control of hypocretin (orexin) neurons and arousal circuits
L de Lecea - Sleep, Neuronal Plasticity and Brain Function, 2015 - Springer
In 1998, our group discovered a cDNA that encoded the precursor of two putative
neuropeptides that we called hypocretins for their hypothalamic expression and their …
neuropeptides that we called hypocretins for their hypothalamic expression and their …
Cortico-autonomic local arousals and heightened somatosensory arousability during NREMS of mice in neuropathic pain
Frequent nightly arousals typical for sleep disorders cause daytime fatigue and present
health risks. As such arousals are often short, partial, or occur locally within the brain …
health risks. As such arousals are often short, partial, or occur locally within the brain …
Microglial TNFα controls daily changes in synaptic GABAARs and sleep slow waves
Microglia sense the changes in their environment. How microglia actively translate these
changes into suitable cues to adapt brain physiology is unknown. We reveal an activity …
changes into suitable cues to adapt brain physiology is unknown. We reveal an activity …
Sleep enhances learning of a functional motor task in young adults
A Al-Sharman, CF Siengsukon - Physical therapy, 2013 - academic.oup.com
Background Sleep has been demonstrated to enhance simple motor skill learning “offline” in
young adults.“Offline learning” refers to either the stabilization or the enhancement of a …
young adults.“Offline learning” refers to either the stabilization or the enhancement of a …
[HTML][HTML] Role of slow oscillatory activity and slow wave sleep in consolidation of episodic-like memory in rats
CN Oyanedel, S Binder, E Kelemen, K Petersen… - Behavioural brain …, 2014 - Elsevier
Our previous experiments showed that sleep in rats enhances consolidation of
hippocampus dependent episodic-like memory, ie the ability to remember an event bound …
hippocampus dependent episodic-like memory, ie the ability to remember an event bound …
[HTML][HTML] Modulation of adult hippocampal neurogenesis by sleep: impact on mental health
C Navarro-Sanchis, O Brock… - Frontiers in neural …, 2017 - frontiersin.org
The process of neurogenesis has been demonstrated to occur throughout life in the
subgranular zone (SGZ) of the hippocampal dentate gyrus of several mammals, including …
subgranular zone (SGZ) of the hippocampal dentate gyrus of several mammals, including …
Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT4 receptor activation (RS67333) on object recognition in mice
T Freret, V Bouet, A Quiedeville, G Nee… - Behavioural brain …, 2012 - Elsevier
Facing inefficiency of current treatments to cure Alzheimer disease (AD), a pharmacological
approach is now emerging on the assumption that a single compound may be able to hit …
approach is now emerging on the assumption that a single compound may be able to hit …
Optical probing of orexin/hypocretin receptor antagonists
Abstract Study Objectives The present study investigated the function of Hypocretin (Hcrt or
Orexin/OX) receptor antagonists in sleep modulation and memory function with optical …
Orexin/OX) receptor antagonists in sleep modulation and memory function with optical …