Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape
that allows their assignment to clusters based on underlying genetic alterations. With around …

Phaeochromocytoma and paraganglioma (PPGL) are chromaffin cell tumours that require
timely diagnosis because of their potentially serious cardiovascular and sometimes life …

A molecular biology–based taxonomy has been proposed for pheochromocytoma and
paraganglioma (PPGL). Data from the Cancer Genome Atlas revealed clinically relevant …

Patients with germline SDHD pathogenic variants (encoding succinate dehydrogenase
subunit D; ie, paraganglioma 1 syndrome) are predominantly affected by head and neck …

Cancer is one of the leading causes of mortality worldwide. PPAR modulators may hold
great potential for the management of cancer patients. Indeed, PPARs are critical sensors …

The paraganglioma (PGL) syndromes types 1–5 are autosomal dominant disorders
characterized by familial predisposition to PGLs, phaeochromocytomas (PCs), renal cell …

Purpose In this study, we aim to evaluate the efficacy and safety of 225 AC-DOTATATE
targeted alpha therapy in advanced-stage paragangliomas (PGLs). Methods Nine (6 males …

Paragangliomas (PGL) develop from the parasympathetic system in the head and neck (HN)
and arise primarily in four distinct areas: Carotid body, vagal, middle ear, and larynx …

Pheochromocytomas/paragangliomas overexpress somatostatin receptors, and recent
studies have already shown excellent results in the localization of sympathetic succinate …

Abstract Context Pheochromocytomas and paragangliomas (PPGLs) are characterized by a
strong genetic component, with up to 40% of patients carrying a germline mutation in a …