Brain-specific deletion of histone variant H2A. z results in cortical neurogenesis defects and neurodevelopmental disorder
Defects in neurogenesis alter brain circuit formations and may lead to neurodevelopmental
disorders such as autism and schizophrenia. Histone H2A. z, a variant of histone H2A, plays …
disorders such as autism and schizophrenia. Histone H2A. z, a variant of histone H2A, plays …
Larval defense against attack from parasitoid wasps requires nociceptive neurons
JL Robertson, A Tsubouchi, WD Tracey - PloS one, 2013 - journals.plos.org
Parasitoid wasps are a fierce predator of Drosophila larvae. Female Leptopilina boulardi
(LB) wasps use a sharp ovipositor to inject eggs into the bodies of Drosophila melanogaster …
(LB) wasps use a sharp ovipositor to inject eggs into the bodies of Drosophila melanogaster …
The role of small GTPases in neuronal morphogenesis and polarity
C Gonzalez‐Billault, P Muñoz‐Llancao… - …, 2012 - Wiley Online Library
The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton
support neuronal morphogenesis. Small RhoGTPases family members have emerged as …
support neuronal morphogenesis. Small RhoGTPases family members have emerged as …
BTBD3 controls dendrite orientation toward active axons in mammalian neocortex
A Matsui, M Tran, AC Yoshida, SS Kikuchi, MU… - Science, 2013 - science.org
Experience-dependent structural changes in the developing brain are fundamental for
proper neural circuit formation. Here, we show that during the development of the sensory …
proper neural circuit formation. Here, we show that during the development of the sensory …
The transmembrane LRR protein DMA-1 promotes dendrite branching and growth in C. elegans
OW Liu, K Shen - Nature neuroscience, 2012 - nature.com
Dendrites often adopt complex branched structures. The development and organization of
these arbors fundamentally determine the potential input and connectivity of a given neuron …
these arbors fundamentally determine the potential input and connectivity of a given neuron …
Deterministic and stochastic rules of branching govern dendrite morphogenesis of sensory neurons
Dendrite morphology is necessary for the correct integration of inputs that neurons receive.
The branching mechanisms allowing neurons to acquire their type-specific morphology …
The branching mechanisms allowing neurons to acquire their type-specific morphology …
MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development
Summary Mammalian Sterile 20 (Ste20)-like kinase 3 (MST3) is a ubiquitously expressed
kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling …
kinase capable of enhancing axon outgrowth. Whether and how MST3 kinase signaling …
[HTML][HTML] MACF1 regulates the migration of pyramidal neurons via microtubule dynamics and GSK-3 signaling
Neuronal migration and subsequent differentiation play critical roles for establishing
functional neural circuitry in the developing brain. However, the molecular mechanisms that …
functional neural circuitry in the developing brain. However, the molecular mechanisms that …
[HTML][HTML] Neuronal filopodia: From stochastic dynamics to robustness of brain morphogenesis
CB Wit, PR Hiesinger - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Brain development relies on dynamic morphogenesis and interactions of neurons. Filopodia
are thin and highly dynamic membrane protrusions that are critically required for neuronal …
are thin and highly dynamic membrane protrusions that are critically required for neuronal …
Positional strategies for connection specificity and synaptic organization in spinal sensory-motor circuits
Proprioceptive sensory axons in the spinal cord form selective connections with motor
neuron partners, but the strategies that confer such selectivity remain uncertain. We show …
neuron partners, but the strategies that confer such selectivity remain uncertain. We show …