As long-term pool feeders, ticks have developed myriad strategies to remain discreetly but
solidly attached to their hosts for the duration of their blood meal. The critical biological …

Ticks require blood meal to complete development and reproduction. Multifunctional tick
salivary glands play a pivotal role in tick feeding and transmission of pathogens. Tick …

Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …

Aedes aegypti mosquitoes are responsible for transmitting many medically important viruses
such as those that cause Zika and dengue. The inoculation of viruses into mosquito bite …

Ticks are unique among hematophagous arthropods by continuous attachment to host skin
and blood feeding for days; complexity and diversity of biologically active molecules …

Tick saliva is a complex mixture of peptidic and non-peptidic molecules that aid
engorgement. The composition of tick saliva changes as feeding progresses and the tick …

Dengue viruses (DENV) are transmitted to humans by the bite of Aedes aegypti or Aedes
albopictus mosquitoes, with millions of infections annually in over 100 countries. The …

Tick sialome is comprised of a rich cocktail of bioactive molecules that function as a tool to
disarm host immunity, assist blood-feeding, and play a vibrant role in pathogen …

Saliva of ticks is arguably the most complex saliva of any animal. This is particularly the case
for ixodid species that feed for many days firmly attached to the same skin site of their …

Mouse and nonhuman primate models now serve as useful platforms to study Zika virus
(ZIKV) pathogenesis, candidate therapies, and vaccines, but they rely on needle inoculation …