Oxymatrine ameliorates osteoarthritis via the Nrf2/NF-κB axis in vitro and in vivo
K Zhou, D Liu, Y Jin, W Xia, P Zhang, Z Zhou - Chemico-Biological …, 2023 - Elsevier
Purpose Osteoarthritis (OA) is a common degenerative joint disorder. Currently, the
underlying etiology of OA is still far from fully elucidated and there is no cure for OA …
underlying etiology of OA is still far from fully elucidated and there is no cure for OA …
Oxymatrine protects articular chondrocytes from IL-1β-induced damage through autophagy activation via AKT/mTOR signaling pathway inhibition
J Lu, J Bian, Y Wang, Y Zhao, X Zhao, G Wang… - Journal of Orthopaedic …, 2024 - Springer
Background Osteoarthritis (OA) is a common degenerative joint disease characterized by
persistent articular cartilage degeneration and synovitis. Oxymatrine (OMT) is a quinzolazine …
persistent articular cartilage degeneration and synovitis. Oxymatrine (OMT) is a quinzolazine …
ASA VI controls osteoarthritis in mice by maintaining mitochondrial homeostasis through Sirtuin 3
J Qiao, C Zhong, Q Zhang, G Yang, S Li, J Jin - International …, 2024 - Elsevier
Objective The aim of this study was to investigate whether ASA VI controls osteoarthritis (OA)
by regulating mitochondrial function. Methods Primary chondrocytes were isolated and …
by regulating mitochondrial function. Methods Primary chondrocytes were isolated and …
Post-Transcriptional Regulator RBM47 Stabilizes FBXO2 mRNA to Advance Osteoarthritis Development: WGCNA Analysis and Experimental Validation
Z Tang, J Li, C Li - Biochemical Genetics, 2023 - Springer
Osteoarthritis (OA) is a common chronic joint degenerative disease and a major cause of
disability in the elderly. However, the current intervention strategies cannot effectively …
disability in the elderly. However, the current intervention strategies cannot effectively …