[HTML][HTML] Evolution of patient-reported outcomes and their role in multiple sclerosis clinical trials

CJ Nowinski, DM Miller, D Cella - Neurotherapeutics, 2017 - Elsevier
Patient-reported outcomes (PROs) are playing an increasing role in multiple sclerosis (MS)
research and practice, and are essential for understanding the effects that MS and MS …

Challenges of cost-effectiveness analyses of novel therapeutics for inherited retinal diseases

KT Jayasundera, RO Abuzaitoun, GD Lacy… - American journal of …, 2022 - Elsevier
Purpose To investigate the challenges and potential improvement strategies of cost-
effectiveness analyses performed for therapeutics targeting inherited retinal diseases …

[HTML][HTML] Study protocol: improving cognition in people with progressive multiple sclerosis: a multi-arm, randomized, blinded, sham-controlled trial of cognitive …

A Feinstein, MP Amato, G Brichetto, J Chataway… - BMC neurology, 2020 - Springer
Background Cognitive dysfunction affects up to 70% of people with progressive MS (PMS). It
can exert a deleterious effect on activities of daily living, employment and relationships …

A systematic review of the literature on the development of condition-specific preference-based measures of health

E Goodwin, C Green - Applied health economics and health policy, 2016 - Springer
Background Health state utility values (HSUVs) are required to calculate quality-adjusted life-
years (QALYs). They are frequently derived from generic preference-based measures of …

The impact of multiple sclerosis severity on health state utility values: evidence from Australia

H Ahmad, BV Taylor, I van der Mei… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: The measurement of health state utility values (HSUVs) for a representative
sample of Australian people with multiple sclerosis (MS) has not previously been performed …

[HTML][HTML] Using the Fatigue Severity Scale to inform healthcare decision-making in multiple sclerosis: mapping to three quality-adjusted life-year measures (EQ-5D-3L …

E Goodwin, A Hawton, C Green - Health and Quality of Life Outcomes, 2019 - Springer
Background Fatigue has a major influence on the quality of life of people with multiple
sclerosis. The Fatigue Severity Scale is a frequently used patient-reported measure of …

[HTML][HTML] Group cognitive rehabilitation to reduce the psychological impact of multiple sclerosis on quality of life: the CRAMMS RCT.

NB Lincoln, LE Bradshaw… - Health Technology …, 2020 - ncbi.nlm.nih.gov
BACKGROUND People with multiple sclerosis have problems with memory and attention.
The effectiveness of cognitive rehabilitation has not been established. OBJECTIVES The …

Measuring the health-related quality of life in Australians with multiple sclerosis using the assessment of quality of life-8-dimension (AQoL-8D) multi-attribute utility …

H Ahmad, I van der Mei, BV Taylor, JA Campbell… - Multiple Sclerosis and …, 2020 - Elsevier
Background Health-related quality of life (HRQoL) has not been assessed in Australians
with multiple sclerosis (MS) using a preferentially sensitive multi-attribute utility instrument …

[HTML][HTML] Vestibular rehabilitation in multiple sclerosis: study protocol for a randomised controlled trial and cost-effectiveness analysis comparing customised with …

J Marsden, M Pavlou, R Dennett, A Gibbon… - BMC neurology, 2020 - Springer
Background Symptoms arising from vestibular system dysfunction are observed in 49–59%
of people with Multiple Sclerosis (MS). Symptoms may include vertigo, dizziness and/or …

[HTML][HTML] Association between disability, cognition, fatigue, EQ-5D-3L domains, and utilities estimated with different Western European value sets in patients with …

J Eriksson, G Kobelt, M Gannedahl, J Berg - Value in Health, 2019 - Elsevier
Objectives To assess the association between fatigue, cognition, domains of the EuroQol
five-dimensional questionnaire (EQ-5D-3L), disability, and utilities estimated with several …