Aberrant production of the prototypical type 2 cytokines, interleukin (IL)-4 and IL-13 has long
been associated with the pathogenesis of allergic disorders. Despite tremendous scientific …

Abstract Interleukin (IL)-4 and IL-13 were discovered approximately 30 years ago and were
immediately linked to allergy and atopic diseases. Since then, new roles for IL-4 and IL-13 …

Background Atopic dermatitis (AD) is characterized by TH 2-dominated skin inflammation
and systemic response to cutaneously encountered antigens. The TH 2 cytokines IL-4 and IL …

Abstract Purpose Interleukin 4 (IL4), interleukin 4 receptor (IL4R) and interleukin 13 (IL13)
play a key role in the pathogenesis of allergy and asthma development. IL4 and IL13 …

Context A negative association between a history of allergy and childhood acute
lymphoblastic leukemia (ALL) has been reported in previous studies, but remains debated …

This study was to investigate the effects of different fractions of Perilla frutescens (Pf) leaves
extracted by water or ethanol on asthma. BALB/c mice sensitized intraperitoneally and …

Abstract Background Interleukin 4 (IL4) is a key cytokine that regulates the inflammatory
cascade in bronchial asthma. We investigated the association between the IL4 and IL4R …

The prevalence of allergic diseases and drug hypersensitivity reactions (DHRs) during
recent years is increasing. Both, allergic diseases and DHRs seem to be related to an …

Introduction IL4 pathway is known to upregulate IgE mediated immune responses and
responsible for the manifestation of Atopic disorders. The current study was aimed to …

Background: Research increasingly suggests that asthma is a familial and hereditary
disorder and that genetic and environmental factors play a key role in its pathogenesis …