Targeting the molecular & cellular pillars of human aging with exercise

J Goh, E Wong, J Soh, AB Maier… - The FEBS …, 2023 - Wiley Online Library
Biological aging is the main driver of age‐associated chronic diseases. In 2014, the United
States National Institute of Aging (NIA) sponsored a meeting between several investigators …

Adherence to the Mediterranean diet and risk of frailty and pre-frailty in elderly adults: A systematic review and dose-response meta-analysis with GRADE assessment

D Poursalehi, K Lotfi, P Saneei - Ageing Research Reviews, 2023 - Elsevier
Background Several studies have explored the association between Mediterranean diet and
frailty, but reported inconsistent results. This systematic review and dose-response meta …

Epidemiology and impact of frailty in patients with atrial fibrillation in Europe

M Proietti, GF Romiti, M Vitolo, SL Harrison… - Age and …, 2022 - academic.oup.com
Background Frailty is a medical syndrome characterised by reduced physiological reserve
and increased vulnerability to stressors. Data regarding the relationship between frailty and …

The relationship between the modified frailty index score (mFI-5), malnutrition, body composition, systemic inflammation and short-term clinical outcomes in patients …

J McGovern, A Grayston, D Coates, S Leadbitter… - BMC geriatrics, 2023 - Springer
Background While the current literature suggests an association with frailty and clinical
outcomes in patients undergoing surgery for colorectal cancer (CRC), the basis of this …

Associations between lifestyle factors and multidimensional frailty: a cross-sectional study among community-dwelling older people

MALM van Assen, JHM Helmink, RJJ Gobbens - BMC geriatrics, 2022 - Springer
Background Multidimensional frailty, including physical, psychological, and social
components, is associated to disability, lower quality of life, increased healthcare utilization …

Every step counts: synthesising reviews associating objectively measured physical activity and sedentary behaviour with clinical outcomes in community-dwelling …

KA Ramsey, CGM Meskers, AB Maier - The Lancet Healthy …, 2021 - thelancet.com
It is unclear which parameters of physical activity and sedentary behaviour are important for
healthy ageing, and to what extent. This Review aimed to synthesise, quantify, and compare …

The prevalence and prognostic value of frailty screening measures in patients undergoing surgery for colorectal cancer: observations from a systematic review

J McGovern, RD Dolan, PG Horgan, BJ Laird… - BMC geriatrics, 2022 - Springer
Introduction Frailty is a complex multifactorial syndrome characterised by a significant
increase in vulnerability and worsened health outcomes. Despite a range of proposed frailty …

Patterns of Accelerometer-Measured Physical Activity and Health Outcomes in Adults: A Systematic Review.

R Brady, WJ Brown, M Hillsdon… - Medicine and science in …, 2022 - europepmc.org
Purpose The aim of this study was to systematically review the literature on accelerometer-
measured physical activity and health outcomes in adults. Methods Eight electronic …

Frailty affects prognosis in patients with colorectal cancer: a systematic review and meta-analysis

M Cai, Z Gao, J Liao, Y Jiang, Y He - Frontiers in Oncology, 2022 - frontiersin.org
Background The prevalence of colorectal cancer has remained high. Most patients have
already developed into the middle and advanced stage when they are diagnosed with …

Analyzing successful aging and longevity: Risk factors and health promoters in 2020 older adults

DA Kashtanova, AN Taraskina, VV Erema… - International journal of …, 2022 - mdpi.com
Geriatric syndromes (GSs) and aging-associated diseases (AADs) are common side effects
of aging. They are affecting the lives of millions of older adults and placing immense …