Global Cancer Statistics 2022: the trends projection analysis

BS Chhikara, K Parang - Chemical Biology Letters, 2023 - pubs.thesciencein.org
Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

[HTML][HTML] Bioactivity and development of small non-platinum metal-based chemotherapeutics

MG Ferraro, M Piccolo, G Misso, R Santamaria, C Irace - Pharmaceutics, 2022 - mdpi.com
Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

[HTML][HTML] Using chitosan or chitosan derivatives in cancer therapy

MS Shakil, KM Mahmud, M Sayem, MS Niloy… - Polysaccharides, 2021 - mdpi.com
Cancer is one of the major causes of death worldwide. Chemotherapeutic drugs have
become a popular choice as anticancer agents. Despite the therapeutic benefits of …

[HTML][HTML] The Prognostic and therapeutic value and clinical implications of fibroblast activation protein-α as a novel biomarker in colorectal cancer

Z Kalaei, R Manafi-Farid, B Rashidi, FK Kiani… - Cell Communication and …, 2023 - Springer
The identification of contributing factors leading to the development of Colorectal Cancer
(CRC), as the third fatal malignancy, is crucial. Today, the tumor microenvironment has been …

[HTML][HTML] The promise of nanoparticles-based radiotherapy in cancer treatment

M Haque, MS Shakil, KM Mahmud - Cancers, 2023 - mdpi.com
Simple Summary Radiotherapy (RT) is used worldwide as a gold standard treatment
approach for cancer management. However, the RT treatment modality contains limitations …

Metal Complexes in cancer treatment: Journey so far

A Kumar Singh, A Kumar, H Singh… - Chemistry & …, 2023 - Wiley Online Library
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …

[HTML][HTML] Molecular design, spectroscopic, DFT, pharmacological, and molecular docking studies of novel ruthenium (III)–Schiff base complex: An inhibitor of …

AFH Noureldeen, SW Aziz, SA Shouman… - International Journal of …, 2022 - mdpi.com
A novel ruthenium (III)–pyrimidine Schiff base was synthesized and characterized using
different analytical and spectroscopic techniques. Molecular geometries of the ligand and …

[HTML][HTML] New nanostructured materials based on mesoporous silica loaded with Ru (II)/Ru (III) complexes with anticancer and antimicrobial properties

G Marinescu, DC Culita, T Mocanu, RA Mitran… - Pharmaceutics, 2023 - mdpi.com
A new series of nanostructured materials was obtained by functionalization of SBA-15
mesoporous silica with Ru (II) and Ru (III) complexes bearing Schiff base ligands derived …

Combination of ruthenium (II) polypyridyl complex Δ-Ru1 and Taxol enhances the anti-cancer effect on Taxol-resistant cancer cells through Caspase-1/GSDMD …

D Chen, S Guo, X Tang, Y Rong, H Bo, H Shen… - Journal of Inorganic …, 2022 - Elsevier
Taxol is the first-line drug for cancer treatment. However, tumor resistance to Taxol is still a
significant challenge in clinical practice. Here, we studied the synergistic effect of a …

Ruthenium complexes bearing glucosyl ligands are able to inhibit the amyloid aggregation of short histidine-peptides

D Florio, S La Manna, A Annunziata, I Iacobucci… - Dalton …, 2023 - pubs.rsc.org
Neurodegenerative diseases are often characterized by the formation of aggregates of
amyloidogenic peptides and proteins, facilitating the formation of neurofibrillary plaques. In …