Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems
DA Subramanian, R Langer, G Traverso - Journal of Nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …
administration which is associated with greater patient medication adherence. One major …
[HTML][HTML] Advances in oral peptide drug nanoparticles for diabetes mellitus treatment
Y Li, W Zhang, R Zhao, X Zhang - Bioactive Materials, 2022 - Elsevier
Peptide drugs play an important role in diabetes mellitus treatment. Oral administration of
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
peptide drugs is a promising strategy for diabetes mellitus because of its convenience and …
Controlled synthesis of in-situ gold nanoparticles onto chitosan functionalized PLGA nanoparticles for oral insulin delivery
HA Asal, KR Shoueir, MA El-Hagrasy… - International Journal of …, 2022 - Elsevier
Chitosan-based nanoparticles (chitosan nanoparticles (ChNps), chitosan gold Nps
(ChAuNps), and chitosan gold Nps functionalized with poly lactic-co-glycolic acid …
(ChAuNps), and chitosan gold Nps functionalized with poly lactic-co-glycolic acid …
[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: Recent advances and future perspectives
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …
[HTML][HTML] Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Oral delivery is the preferred route of drug administration due to patient compliance and
convenience. Despite this, nanomedicines have so far primarily been developed for the …
convenience. Despite this, nanomedicines have so far primarily been developed for the …
Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport
V Lenders, X Koutsoumpou, P Phan… - Chemical Society …, 2023 - pubs.rsc.org
The biomedical use of nanoparticles (NPs) has been the focus of intense research for over a
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …
decade. As most NPs are explored as carriers to alter the biodistribution, pharmacokinetics …
Mucoadhesive and mucus-penetrating interpolyelectrolyte complexes for nose-to-brain drug delivery
NN Porfiryeva, II Semina, IA Salakhov… - … , Biology and Medicine, 2021 - Elsevier
Nasal administration offers a possibility of delivering drugs to the brain. In the present work,
nasal drug delivery systems were designed based on cationic Eudragit® EPO (EPO) and …
nasal drug delivery systems were designed based on cationic Eudragit® EPO (EPO) and …
Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin
Vancomycin (Van) is a key antibiotic of choice for the treatment of systemic methicillin
resistant Staphylococcus aureus (MRSA) infections. However, due to its poor membrane …
resistant Staphylococcus aureus (MRSA) infections. However, due to its poor membrane …
Critical material designs for mucus-and mucosa-penetrating oral insulin nanoparticle development
Subcutaneous and pulmonary insulin is associated with medical and pharmaceutical
complications. Oral insulin mimics physiological glucose regulation with reduced …
complications. Oral insulin mimics physiological glucose regulation with reduced …
Advances in regulating physicochemical properties of mesoporous silica nanocarriers to overcome biological barriers
Y Wang, K Gou, X Guo, J Ke, S Li, H Li - Acta Biomaterialia, 2021 - Elsevier
Mesoporous silica nanoparticles (MSNs) with remarkable structural features have been
proven to be an excellent platform for the delivery of therapeutic molecules. Biological …
proven to be an excellent platform for the delivery of therapeutic molecules. Biological …