The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …

Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Background The popularity of applying intermittent fasting (IF) has increased as more and
more people are trying to avoid or alleviate obesity and metabolic disease. This study aimed …

The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a
hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused …

The antiphospholipid syndrome (APS) was fully recognized as a clinical entity in the early
1980s. Still, more than 30 years later, the epidemiology of APS is not well described, and …

Background Little is known about fibrin clot composition in relation to its structure and
lysability. We investigated plasma clots protein composition and its associations with clot …

Background: Elevated plasma lactate levels correlate with high mortality rate in acute
pulmonary embolism (PE) patients. We hypothesized that elevated lactate levels correlate …

It has been reported that 476 proteins can be detected in plasma fibrin clots from patients
with venous thromboembolism. Plasma fibrin clots proteomic composition in relation to their …

Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) are two related
autoimmune diseases. In recent years, there has been sufficient evidence to suggest that …

Proteomics, the simultaneous study of all proteins in a given cell, tissue or organism, is an
innovative approach used to identify novel markers for diagnosis, prognosis and the …