Osteoporosis is considered an age-related disorder of the skeletal system, characterized
primarily by decreased bone mineral density (BMD), microstructural quality and an elevated …

Osteoporosis resulting from an imbalance of bone turnover between resorption and
formation is a critical health issue worldwide. Estrogen deficiency following a nature aging …

Skeletal tissue is highly innervated. Although different types of nerves have been recently
identified in the bone, the crosstalk between bone and nerves remains unclear. In this …

Age-related chronic diseases are an enormous burden to modern societies worldwide.
Among these, osteoporosis, a condition that predisposes individuals to an increased risk of …

Osteoporosis is becoming a major concern in the field of public health. The process of bone
loss is insidious and does not directly induce obvious symptoms. Complications indicate an …

The imbalance between osteogenesis and osteoclastogenesis is a feature of bone
metabolic disease. Cadmium (Cd) exposure causes human bone loss and osteoporosis …

Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …

Improving the ability of implants to integrate with natural bone tissue at the initial stage of
implantation remains a huge challenge because bone-to-implant interfaces are often …

Oxidative stress and autophagy play essential roles in the development of senile
osteoporosis which is characterized by disrupted osteoclastic bone resorption and …

Blocking the reactive oxygen species (ROS) induced osteoblast senescence and massive
RANKL release is the key to alleviate the vicious osteoporotic micro-environment in aged …