Perspectives and Advances in the Understanding of Tuberculosis

RL Kinsella, DX Zhu, GA Harrison… - Annual Review of …, 2021 - annualreviews.org
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a
leading cause of death due to infection in humans. To more effectively combat this …

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

BA Rosa, M Ahmed, DK Singh… - Communications …, 2021 - nature.com
SARS-CoV-2 virus has infected more than 92 million people worldwide resulting in the
Coronavirus disease 2019 (COVID-19). Using a rhesus macaque model of SARS-CoV-2 …

A single‐nucleus transcriptomics study of alcohol use disorder in the nucleus accumbens

EJCG van den Oord, LY Xie, M Zhao… - Addiction …, 2023 - Wiley Online Library
Gene expression studies offer promising opportunities to better understand the processes
underlying alcohol use disorder (AUD). As cell types differ in their function, gene expression …

Metabolic changes enhance necroptosis of type 2 diabetes mellitus mice infected with Mycobacterium tuberculosis

A Vankayalapati, O Durojaye, T Mukherjee… - Plos …, 2024 - journals.plos.org
Previously, we found that Mycobacterium tuberculosis (Mtb) infection in type 2 diabetes
mellitus (T2DM) mice enhances inflammatory cytokine production which drives pathological …

In-depth systems biological evaluation of bovine alveolar macrophages suggests novel insights into molecular mechanisms underlying Mycobacterium bovis infection

A Hasankhani, A Bahrami, S Mackie… - Frontiers in …, 2022 - frontiersin.org
Objective Bovine tuberculosis (bTB) is a chronic respiratory infectious disease of domestic
livestock caused by intracellular Mycobacterium bovis infection, which causes~ $3 billion in …

[HTML][HTML] BCG vaccination reduces the mortality of Mycobacterium tuberculosis–infected type 2 diabetes mellitus mice

RK Radhakrishnan, RS Thandi, D Tripathi… - JCI insight, 2020 - ncbi.nlm.nih.gov
Diabetes is a significant risk factor for the development of active tuberculosis. In this study,
we used a mouse model of type 2 diabetes mellitus (T2DM) to determine the effect of prior …

The role of cigarette smoking and alcohol consumption in pulmonary tuberculosis development and recurrence

M Lampalo, I Jukić, J Bingulac-Popović… - Acta Clinica …, 2019 - hrcak.srce.hr
Sažetak During a two-year period (2001-2003), 464 patients were treated for tuberculosis at
Jordanovac Department for Lung Diseases in Croatia. Besides pulmonary tuberculosis in …

[HTML][HTML] Analysis of factors of pulmonary fungal infection in mice in respiratory medicine department based on logistic regression analysis model and Progranulin

J Wang, Q Zu, W Wang - Saudi Journal of Biological Sciences, 2020 - Elsevier
The objective of this research is to solve the current medical problems of a high incidence of
fungal infections in the lungs, high misdiagnosis rate, and high mortality. In this study, firstly …

Association of gene polymorphisms and environmental factors in tuberculosis patients and their household contacts

Y Chen, WH Peng, SF Lai, F Luo, D Luo… - Transactions of The …, 2021 - academic.oup.com
Background Tuberculosis (TB) is an important public health problem in China and
environmental and genetic factors have an impact on its occurrence and development. We …

Vitamin B12 and coenzyme Q10 ameliorated alcohol-driven impairment of hematological parameters, inflammation, and organ damage in a mouse model

B Kipchumba, AO Isaac, VK Mwaeni, G Omwenga… - Nutrire, 2023 - Springer
Introduction Chronic alcohol consumption is associated with a myriad of negative
physiological and biochemical changes in humans. Vitamin B12 and coenzyme Q10 …