Diagnosis and management of glioblastoma: A comprehensive perspective

V Gilard, A Tebani, I Dabaj, A Laquerrière… - Journal of personalized …, 2021 - mdpi.com
Glioblastoma is the most common malignant brain tumor in adults. The current management
relies on surgical resection and adjuvant radiotherapy and chemotherapy. Despite …

[HTML][HTML] Overview of prognostic factors in adult gliomas

A Sharma, JJ Graber - Annals of palliative medicine, 2021 - apm.amegroups.org
Gliomas represent the majority of malignant central nervous system tumors, with the most
aggressive subtype, glioblastoma, accounting for almost 57% of this entity. Type of glioma …

Functional outcomes and health-related quality of life following glioma surgery

PCDW Hamer, M Klein, SL Hervey-Jumper… - …, 2021 - journals.lww.com
Functional outcome following glioma surgery is defined as how the patient functions or feels.
Functional outcome is a coprimary end point of surgery in patients with diffuse glioma …

Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update

JS Domino, DR Ormond, IM Germano, M Sami… - Journal of neuro …, 2020 - Springer
Target population These recommendations apply to adults with newly diagnosed or
suspected glioblastoma. Question What is the effect of extent of surgical resection on patient …

Prognostic analysis and nomogram construction for older patients with IDH-wild-type glioblastoma

W Cao, L Xiong, L Meng, Z Li, Z Hu, H Lei, J Wu… - Heliyon, 2023 - cell.com
As many countries face an ageing population, the number of older patients with
glioblastoma (GB) is increasing. Thus, there is an urgent need for prognostic models to aid …

Viral vector: potential therapeutic for glioblastoma multiforme

C Manikandan, A Kaushik, D Sen - Cancer Gene Therapy, 2020 - nature.com
Glioblastoma multiforme is a highly malignant primary brain tumour found in adults and is
highlighted as the most devastating among all the other grades of glioma. Well-established …

The surgical perspective in precision treatment of diffuse gliomas

N Thon, JC Tonn, FW Kreth - OncoTargets and therapy, 2019 - Taylor & Francis
Over the last decade, advances in molecular and imaging-based biomarkers have induced
a more versatile diagnostic classification and prognostic evaluation of glioma patients. This …

Surgeon experience in glioblastoma surgery of the elderly—a multicenter, retrospective cohort study

JP Pöppe, L Machegger, J Steinbacher… - Journal of Neuro …, 2023 - Springer
Purpose To assess the impact of individual surgeon experience on overall survival (OS),
extent of resection (EOR) and surgery-related morbidity in elderly patients with glioblastoma …

Insurance type impacts the economic burden and survival of patients with newly diagnosed glioblastoma

A Chandra, JS Young, C Dalle Ore, F Dayani… - Journal of …, 2019 - thejns.org
OBJECTIVE Glioblastoma (GBM) carries a high economic burden for patients and
caregivers, much of which is associated with initial surgery. The authors investigated the …

Extent of resection and survival outcomes of geriatric patients with glioblastoma: is there benefit from aggressive surgery?

V Lopez-Rivera, A Dono, CT Lewis, A Chandra… - Clinical Neurology and …, 2021 - Elsevier
Objective We examine the impact of age and extent of resection (EOR) on overall survival
(OS) in geriatric patients with Glioblastoma (GBM). Methods The SEER 18 Registries was …