Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …

Abstract Background Circular RNAs (circRNAs) are involved in regulatory processes of
ubiquitination and deubiquitination in various tumors at post-transcriptional epigenetic …

Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …

Circular RNA (circRNA), a novel type of covalently closed RNA, is implicated in several
developmental and metabolic disease processes. CircRNAs exhibit tissue-specific …

Age-related macular degeneration (AMD) is an ever-increasing, insidious disease which
reduces the quality of life of millions of elderly people around the world. AMD is …

PAX5, a member of the Paired Box (PAX) transcription factor family, is an essential factor for
B-lineage identity during lymphoid differentiation. Mechanistically, PAX5 controls gene …

As a novel form of regulated cell death, ferroptosis is characterized by intracellular iron and
lipid peroxide accumulation, which is different from other regulated cell death forms …

Background Pancreatic cancer (PC) is an extremely malignant tumor with low survival rate.
Effective biomarkers and therapeutic targets for PC are lacking. The roles of circular RNAs …

Glioblastoma (GBM) is one of the most devastating cancers and is characterized by rapid
cell proliferation and aggressive invasiveness. Legumain (LGMN), a substrate-specific …