Current trend in antiviral therapy for chronic hepatitis B

RN Chien, YF Liaw - Viruses, 2022 - mdpi.com
Since active hepatitis B virus (HBV) replication is the key driver of hepatic necroinflammation
and disease progression, the treatment aim of chronic hepatitis B (CHB) is to suppress HBV …

Host genetic determinants of hepatitis B virus infection

Z Zhang, C Wang, Z Liu, G Zou, J Li, M Lu - Frontiers in genetics, 2019 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is still a major health problem worldwide. Recently,
a great number of genetic studies based on single nucleotide polymorphisms (SNPs) and …

Association between fatty liver and cirrhosis, hepatocellular carcinoma, and hepatitis B surface antigen seroclearance in chronic hepatitis B

J Li, HI Yang, ML Yeh, MH Le, AK Le… - The Journal of …, 2021 - academic.oup.com
Abstract Background Chronic hepatitis B (CHB) and fatty liver (FL) are common, natural
history data on concurrent FL and CHB (FL-CHB) are limited. This study aimed to evaluate …

[HTML][HTML] 2020 Taiwan consensus statement on the management of hepatitis C: Part (II) special populations

ML Yu, PJ Chen, CY Dai, TH Hu, CF Huang… - Journal of the Formosan …, 2020 - Elsevier
Hepatitis C virus (HCV) infection is a silent killer that leads to rapid progression of liver
cirrhosis and hepatocellular carcinoma (HCC). High prevalence of HCV infection has been …

An expert review on the use of tenofovir alafenamide for the treatment of chronic hepatitis B virus infection in Asia

MR Charlton, A Alam, A Shukla, B Dashtseren… - Journal of …, 2020 - Springer
Asia has intermediate-to-high prevalence and high morbidity of hepatitis B virus (HBV)
infection. The use of guideline-recommended nucleos (t) ide analogs with high barrier to …

Once-daily tenofovir disoproxil fumarate in treatment-naive Taiwanese patients with chronic hepatitis B and minimally raised alanine aminotransferase (TORCH-B): a …

YC Hsu, CY Chen, IW Chang, CY Chang… - The Lancet Infectious …, 2021 - thelancet.com
Background Antiviral therapy for patients with non-cirrhotic chronic hepatitis B and minimally
raised alanine aminotransferase (ALT) is controversial. We aimed to investigate the efficacy …

Reactivation of hepatitis B virus infection in patients with rheumatoid arthritis receiving tofacitinib

ST Wang, CW Tseng, CW Hsu, CH Tung… - … journal of rheumatic …, 2021 - Wiley Online Library
Objectives The aim of this study was to investigate hepatitis B virus (HBV) reactivation in
patients with rheumatoid arthritis (RA) receiving tofacitinib. Method This was a retrospective …

Role of hepatitis D virus infection in development of hepatocellular carcinoma among chronic hepatitis B patients treated with nucleotide/nucleoside analogues

TY Jang, YJ Wei, TW Liu, ML Yeh, SF Liu, CT Hsu… - Scientific Reports, 2021 - nature.com
Hepatitis D virus (HDV) infection increases the risk of hepatocellular carcinoma (HCC) in the
natural course of chronic hepatitis B (CHB) patients. Its role in patients treated with …

Elimination of hepatitis B in highly endemic settings: lessons learned in Taiwan and challenges ahead

CJ Liu, PJ Chen - Viruses, 2020 - mdpi.com
Hepatitis B virus (HBV) infection and its related liver diseases are important health problems
worldwide, particularly in the Asia-Pacific region. For the past 4–5 decades, Taiwan's …

Sex and ethnic disparities in hepatitis B evaluation and treatment across the world

S Kudaravalli, DQ Huang, ML Yeh, L Trinh, PC Tsai… - Journal of …, 2024 - Elsevier
Background & Aims Oral antiviral therapy with nucleos (t) ide analogues (NAs) for chronic
hepatitis B (CHB) is well-tolerated and lifesaving, but real-world data on utilization are …