[HTML][HTML] Oral biofilms from symbiotic to pathogenic interactions and associated disease–connection of periodontitis and rheumatic arthritis by peptidylarginine …

K Kriebel, C Hieke, B Müller-Hilke, M Nakata… - Frontiers in …, 2018 - frontiersin.org
A wide range of bacterial species are harbored in the oral cavity, with the resulting complex
network of interactions between the microbiome and host contributing to physiological as …

[HTML][HTML] Unmet needs and perspectives in oral cancer prevention

J Bouaoud, P Bossi, M Elkabets, S Schmitz… - Cancers, 2022 - mdpi.com
Simple Summary Oral cavity is the most common site of head and neck cancer which is
ranked as the eighth most common cancer worldwide. Oral cancer treatment is often …

Modeling Crevicular Fluid Flow and Host‐Oral Microbiome Interactions in a Gingival Crevice‐on‐Chip

H Makkar, Y Zhou, KS Tan, CT Lim… - Advanced Healthcare …, 2023 - Wiley Online Library
Gingival crevice and gingival crevicular fluid (GCF) flow play a crucial role at the gingiva‐
oral microbiome interface which contributes toward maintaining the balance between …

Mechanisms of vascular damage by systemic dissemination of the oral pathogen Porphyromonas gingivalis

C Farrugia, GP Stafford, J Potempa… - The FEBS …, 2021 - Wiley Online Library
Several studies have shown a clear association between periodontal disease and increased
risk of cardiovascular disease. Porphyromonas gingivalis (Pg), a key oral pathogen, and its …

[HTML][HTML] The three-dimensional in vitro cell culture models in the study of oral cancer immune microenvironment

E Dalir Abdolahinia, X Han - Cancers, 2023 - mdpi.com
Simple Summary The extensive array of applications in 3D culture models closely mimics
the precise physiological conditions of in vivo settings, enabling the investigation of …

[HTML][HTML] Multi-species oral biofilm promotes reconstructed human gingiva epithelial barrier function

L Shang, D Deng, JK Buskermolen, MM Janus… - Scientific reports, 2018 - nature.com
Since the oral mucosa is continuously exposed to abundant microbes, one of its most
important defense features is a highly proliferative, thick, stratified epithelium. The cellular …

Oral microbiome interactions with gingival gene expression patterns for apoptosis, autophagy and hypoxia pathways in progressing periodontitis

JL Ebersole, SS Kirakodu, OA Gonzalez - Immunology, 2021 - Wiley Online Library
Oral mucosal tissues must react with and respond to microbes comprising the oral
microbiome ecology. This study examined the interaction of the microbiome with …

The mucosal pellicle–An underestimated factor in oral physiology

C Hannig, M Hannig, A Kensche, G Carpenter - Archives of oral biology, 2017 - Elsevier
Bioadhesion and bio-adsorption of proteins, glycoproteins and other biomolecules are
ubiquitous phenomena in the oral cavity. While the protective role of the adsorbed salivary …

A review of co-culture models to study the oral microenvironment and disease

SE Mountcastle, SC Cox, RL Sammons… - Journal of oral …, 2020 - Taylor & Francis
Co-cultures allow for the study of cell–cell interactions between different eukaryotic species
or with bacteria. Such an approach has enabled researchers to more closely mimic complex …

Differential immune responses of 3D gingival and periodontal connective tissue equivalents to microbial colonization

H Makkar, S Atkuru, YL Tang, T Sethi… - Journal of Tissue …, 2022 - journals.sagepub.com
Gingival and periodontal ligament fibroblasts are functionally distinct cell types within the
dento-gingival unit that participate in host immune response. Their microenvironment …