Migraine and neuropathic pain (NP) are both painful, disabling, chronic conditions which
exhibit some symptom similarities and are thus considered to share a common etiology. The …

Calcitonin gene-related peptide-targeted monoclonal antibodies (CGRP mAbs) are
increasingly being used as preventive treatments for migraine. Their effectiveness and …

Migraine is a neurovascular disorder that can be debilitating for individuals and society.
Current research focuses on finding effective analgesics and management strategies for …

Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …

Migraine is a debilitating neurological disorder characterized by recurring episodes of
throbbing headaches that are frequently accompanied by sensory disturbances, nausea …

OnabotulinumtoxinA (BT-A) is one of the few drugs approved for the preventive treatment of
chronic migraine (CM). Despite this, some aspects of its mechanism of action are still a …

Migraine pain is frequently accompanied by cranial hyperalgesia and allodynia. Calcitonin
gene-related peptide (CGRP) is implicated in migraine pathophysiology but its role in facial …

Background Migraine prevalence and levels of calcitonin gene-related peptide (CGRP), a
peptide involved in migraine pathophysiology, differ between men and women, and appear …

Treatment with the anti-CGRP antibody fremanezumab is successful in the prevention of
chronic and frequent episodic migraine. In preclinical rat experiments, fremanezumab has …

Background Women are disproportionately affected by migraine, representing up to 75% of
all migraine cases. This discrepancy has been proposed to be influenced by differences in …