Aging, oxidative stress and degenerative diseases: mechanisms, complications and emerging therapeutic strategies

MR Chaudhary, S Chaudhary, Y Sharma, TA Singh… - Biogerontology, 2023 - Springer
Aging accompanied by several age-related complications, is a multifaceted inevitable
biological progression involving various genetic, environmental, and lifestyle factors. The …

Rheumatoid arthritis and the risk of preterm birth

RMG Falcon, RMU Alcazar… - American Journal of …, 2023 - Wiley Online Library
During pregnancy, many diseases are correlated with different adverse outcomes. In turn,
pregnancy affects the body, leading to increased disease susceptibility. This interplay …

Exposure to pesticide components causes recurrent pregnancy loss by increasing placental oxidative stress and apoptosis: a case–control study.

MAH El-Baz, AF Amin, KM Mohany - Scientific Reports, 2023 - search.ebscohost.com
We investigated the plasma levels of pesticides components namely polychlorinated
biphenyls (PCBs), dieldrin, dichlorodiphenyldichloroethylene (DDE), ethion, malathion, and …

Toxic metals in human milk in relation to tobacco smoke exposure

M Szukalska, TA Merritt, W Lorenc, K Sroczyńska… - Environmental …, 2021 - Elsevier
Several reports confirm the deleterious effects of tobacco smoking and exposure to second-
hand smoke (SHS) resulting in changes in the composition of breast milk. The aim of our …

[HTML][HTML] Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response

MC Shepherd, E Radnaa, OA Tantengco… - Cell Communication and …, 2021 - Springer
Background Fetal cell-derived exosomes (extracellular vesicles, 40–160 nm) are
communication channels that can signal parturition by inducing inflammatory changes in …

Association of prenatal essential metal exposure with newborn mitochondrial DNA copy number: Results from a birth cohort study

J Bi, L Song, M Wu, Q Liu, L Xu, G Fan, Z Cao… - Reproductive …, 2023 - Elsevier
Imbalance or deficiencies of essential metals can lead to oxidative stress, that can damage
mitochondrial DNA (mtDNA) molecule. Knowledge on effects of exposure to essential metals …

[PDF][PDF] Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease

R Zhao, L Cao, WJ Gu, L Li, ZZ Chen, J Xiang… - Cell Reports …, 2023 - cell.com
Dysregulated maternal fatty acid metabolism increases the risk of congenital heart disease
(CHD) in offspring with an unknown mechanism, and the effect of folic acid fortification in …

[HTML][HTML] Medication use during pregnancy and the risk of gastroschisis: a systematic review and meta-analysis of observational studies

S Baldacci, M Santoro, L Mezzasalma, A Pierini… - Orphanet Journal of …, 2024 - Springer
Objectives The aetiology of gastroschisis is considered multifactorial. We conducted a
systematic review and meta-analysis to assess whether the use of medications during …

Melatonin‐Attenuated Oxidative Stress in High‐Risk Pregnant Women Receiving Enoxaparin and Aspirin

N Azarmehr, R Porhemat, N Roustaei… - Evidence‐Based …, 2023 - Wiley Online Library
Objective. In pregnancy, reducing inflammation and oxidative stress is important.
Administration of melatonin during pregnancy can improve reproductive performance by …

[PDF][PDF] Antioxidants and Pregnancy: Impact on Maternal and Fetal Health

EI Obeagu, GU Obeagu, J Obiezu… - APPLIED SCIENCES …, 2023 - academia.edu
Pregnancy represents a physiological state characterized by increased metabolic demands
and heightened oxidative stress, posing potential risks to both maternal health and fetal …