Small molecule metabolites: discovery of biomarkers and therapeutic targets
S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …
[HTML][HTML] Smartphone-based platforms implementing microfluidic detection with image-based artificial intelligence
The frequent outbreak of global infectious diseases has prompted the development of rapid
and effective diagnostic tools for the early screening of potential patients in point-of-care …
and effective diagnostic tools for the early screening of potential patients in point-of-care …
Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints
High-performance metabolic analysis is emerging in the diagnosis and prognosis of breast
cancer (BrCa). Still, advanced tools are in demand to deliver the application potentials of …
cancer (BrCa). Still, advanced tools are in demand to deliver the application potentials of …
Comprehensive metabolic fingerprints characterize neuromyelitis optica spectrum disorder by nanoparticle-enhanced laser desorption/ionization mass spectrometry
Timely screening of neuromyelitis optica spectrum disorder (NMOSD) and differential
diagnosis from myelin oligodendrocyte glycoprotein associated disorder (MOGAD) are the …
diagnosis from myelin oligodendrocyte glycoprotein associated disorder (MOGAD) are the …
Plasmonic alloys reveal a distinct metabolic phenotype of early gastric cancer
H Su, X Li, L Huang, J Cao, M Zhang… - Advanced …, 2021 - Wiley Online Library
Gastric cancer (GC) is a multifactorial process, accompanied by alterations in metabolic
pathways. Non‐invasive metabolic profiling facilitates GC diagnosis at early stage leading to …
pathways. Non‐invasive metabolic profiling facilitates GC diagnosis at early stage leading to …
Wearable chemical sensors for biomarker discovery in the omics era
JR Sempionatto, JA Lasalde-Ramírez… - Nature Reviews …, 2022 - nature.com
Biomarkers are crucial biological indicators in medical diagnostics and therapy. However,
the process of biomarker discovery and validation is hindered by a lack of standardized …
the process of biomarker discovery and validation is hindered by a lack of standardized …
Novel research and future prospects of artificial intelligence in cancer diagnosis and treatment
C Zhang, J Xu, R Tang, J Yang, W Wang, X Yu… - Journal of Hematology & …, 2023 - Springer
Research into the potential benefits of artificial intelligence for comprehending the intricate
biology of cancer has grown as a result of the widespread use of deep learning and …
biology of cancer has grown as a result of the widespread use of deep learning and …
Integrative serum metabolic fingerprints based multi‐modal platforms for lung adenocarcinoma early detection and pulmonary nodule classification
L Wang, M Zhang, X Pan, M Zhao, L Huang… - Advanced …, 2022 - Wiley Online Library
Identification of novel non‐invasive biomarkers is critical for the early diagnosis of lung
adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule …
adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule …
Serum metabolic fingerprints on bowl-shaped submicroreactor chip for chemotherapy monitoring
Chemotherapy is a primary cancer treatment strategy, the monitoring of which is critical to
enhancing the survival rate and quality of life of cancer patients. However, current …
enhancing the survival rate and quality of life of cancer patients. However, current …
Impact of cancer metabolism on therapy resistance–clinical implications
AC Gonçalves, E Richiardone, J Jorge, B Polónia… - Drug Resistance …, 2021 - Elsevier
Despite an increasing arsenal of anticancer therapies, many patients continue to have poor
outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of …
outcomes due to the therapeutic failures and tumor relapses. Indeed, the clinical efficacy of …